Papers pre-2000

Design, Synthesis and Evaluation of Inhibitors of Trypanosomal and Leishmanial Dihydrofolate Reductase. Chowdhury, S. F.; Bernier Villamor, V.; Hurtado Guerrero, R.; Leal, I.; Brun, R.; Croft, S. L.; Goodman, J. M.; Maes, L.; Ruiz-Perez, L. M.; Gonzalez Pacanowska, D.; Gilbert, I. H. J. Med. Chem., 1999, 42 , 4300-4312.  link to journal abstract in pubmed  link to the journal where paper was published

The Design and Synthesis of Lipophilic, Phosphoramidate d4T-MP Prodrugs Expressing High Potency Against HIV in Cell Culture: Structural Determinants for in vitro Activity and QSAR. Siddiqui, A.; McGuigan, C.; Gilbert, I.H.; Ballatore, C.; Zuccotto, F.; De Clercq, E.; Balzarini, J. J. Med. Chem., 1999,42, 4122-4128.  link to journal abstract in pubmed  link to the journal where paper was published

Inhibitors of Protease-Resistant Prion Formation. Gilbert I. H.; Rudyk, H.; International Antiviral News, 1999, 7, 78-82.

The Structure-Based Design And Synthesis Of Selective Inhibitors of Trypanosoma cruzi Dihydrofolate Reductase. Zuccotto, F.; Brun, R.; Gonzalez Pacanowska, D.; Ruiz Perez, L. M.; Gilbert, I. H. Bioorg. Med. Chem. Lett., 1999, 9, 1463-1468.  link to journal abstract in pubmed  link to the journal where paper was published

General Synthesis of 3-Phosphorylated myo-Inositol Phospholipids and their Derivatives. Painter, G. F.; Grove, S. J. A.; Gilbert, I. H.; Holmes, A. B.; Raithby, P. R.; Hill, M. L.; Hawkins, P. T.; Stephens, L. R. J. Chem. Soc., Perk. T 1, 1999, 923-936.  link to the journal where paper was published

Design And Synthesis Of Bio-Isosteres Of Thymidine Triphosphate. Goldring, A. O.; Balzarini, J.; Gilbert, I. H. Bioorg. Med. Chem. Lett., 1998, 8, 1211-1215.  link to journal abstract in pubmed  link to the journal where paper was published

An Approach To Use An Unusual Adenosine Transporter To Selectively Deliver Polyamine Analogues To Trypanosomes. Tye, C.-K.; Kasinathan, G.; Barrett, M. P.; Brun, R.; Doyle, V. E.; Fairlamb, A. H.; Weaver R.; Gilbert, I. H. Bioorg. Med. Chem. Lett., 1998, 8, 811-816.  link to journal abstract in pubmed  link to the journal where paper was published

Electrospray Mass Spectrometry For Assay of Erythromycin A Extracted From Fermentation Liquor. Morgan, J.; Rowlands, R. T.; Joyce-Menekse, M. E.; Gilbert, I. H.; Lloyd, D. Biotechnol. Tech., 1998, 12, 435-438.  link to the journal where paper was published

Dihydrofolate Reductase: a Potential Drug Target in Trypanosomes and Leishmania. Zuccotto, F.; Martin, A. C. R.; Laskowski, R. A.; Thornton, J. M.; Gilbert, I. H. J. Comput. Aid. Mol. Des., 1998, 12, 241-257.  link to journal abstract in pubmed  link to the journal where paper was published

Versatile Synthesis of myo-Inositol Phospholipid Precursors. Grove, S. J. A.; Gilbert, I. H.; Holmes, A. B.; Painter, G. F.; Hill, M. L. Chem. Commun., 1997, 1633-1634.  link to the journal where paper was published

The Design and Synthesis of Nucleoside Triphosphate Isosteres as Potential Inhibitors of HIV Reverse Transcriptase. R. Weaver, I. H. Gilbert, Tetrahedron, 1997, 53, 5537-5562.  link to the journal where paper was published

Lipophilic Bioisosteres of Nucleoside Triphosphates. Goldring, A. O.; Gilbert, I. H.; Mahmood, N.; Balzarini, J. Bioorg. Med. Chem. Lett., 1996, 6, 2411-2416.  link to the journal where paper was published

Isosteres of Nucleoside Triphosphates. Weaver, R.; Gilbert, I. H.; Mahmood, N.; Balzarini, J. Bioorg. Med. Chem. Lett., 1996, 6, 2405-2410.

Synthesis of β -Keto and αβ -Unsaturated N-Acetylcysteamine Thioesters. Gilbert, I. H.; Ginty, M.; O’Neill, J. A.; Simpson, T. J.; Staunton J.; Willis C. L. Bioorg. Med. Chem. Lett, 1995, 5, 1587-1590.

Imidazolines as Amide Bond Replacements. Gilbert, I. H.; Rees, D. C.; Crockett, A. K.; Jones, R. C. F. Tetrahedron, 1995, 51, 6315-6335.  link to the journal where paper was published

Synthesis of a Homochiral Alpha, Alpha-Disubstituted Alpha, Beta-Diamino-Acid. Jones, R. C. F.; Crockett, A. K.; Rees D. C.; Gilbert, I. H.  Tetrahedron-Asymmetr., 1994, 5, 1661-1664.

Lewis Acid Catalysed rearrangements of myo-inositol orthoformate derivatives. Gilbert, I. H.  Holmes, A. B.; Pestchanker, M. J.; Young, R. C. Carbohyd. Res., 1992, 234, 117-130.  link to the journal where paper was published

Amide bond replacements: incorporation of a 2,5,5-trisubstituted imidazoline into dipeptides and into a CCK-4 derivative. Gilbert, I. H.; Rees, D. C.; Richardson, R. S. Tetrahedron Lett., 1991, 32, 2277-2280.  link to the journal where paper was published

Synthesis of Protected myo-Inositols. Gilbert, I. H.; Holmes, A. B.; Young, R. C. Tetrahedron Lett., 1990, 31, 2633-2634.

Top