Papers 2005

Interaction of Monobenzamidine-Linked Trypanocides with the Trypanosoma brucei P2 Aminopurine Transporter, Stewart, M. L.; Boussard, C.; Brun, R.; Gilbert, I. H.; Barrett, M. P. Antimicrob. Agents Chemother., 2005, 49, 5169-5171. link to journal abstract in pubmed link to the journal where paper was published

Effects of Inhibitors of [Delta]24(25)-Sterol Methyl Transferase on the Ultrastructure of Epimastigotes of Trypanosoma cruzi. Braga, M. V.; Magaraci, F.; Orenes Lorente, S.; Gilbert, I. H.; de Souza, W. Microsc. Microanal., 2005, 11, 506-511. link to journal abstract in pubmed link to the journal where paper was published

Analogs of Thiolactomycin as Potential Antimalarial Agents. Jones, S. M.; Urch, J. E.; Kaiser, M.; Brun, R.; Harwood, J. L.; Berry, C.; Gilbert, I. H. J. Med. Chem.,2005, 48, 5932-5941. link to journal abstract in pubmed link to the journal where paper was published

Deoxyuridine Triphosphate Nucleotidohydrolase as a Potential Antiparasitic Drug Target. Nguyen, C.; Kasinathan, G.; Leal-Cortijo, I.; Musso-Buendia, A.; Kaiser, M.; Brun, R.; Ruiz-Pérez, L. M.; Johansson, N. G.; González-Pacanowska, D.; Gilbert, I. H. J. Med. Chem., 2005, 48, 5942-5954. link to journal abstract in pubmed link to the journal where paper was published

Design and synthesis of a series of melamine-based nitroheterocycles with activity against trypanosomatid parasites. B aliani, A.; Jimenez Bueno, G.; Stewart, M. L.; Yardley, V.; Brun, R.; Barrett, M. P.; Gilbert, I. H. J. Med. Chem., 2005, 48, 5570-5579. link to journal abstract in pubmed link to the journal where paper was published

Preparation of Transition-State Analogues of Sterol 24-Methyl Transferase as Potential Anti-Parasitics. Orenes Lorente, S.; Jimenez Jimenez, C.; Gros, L.; Yardley, V.; de Luca-Fradley, K.; Croft, S. L.; Urbina, J. A.; Ruiz-Perez, L. M.; Gonzalez Pacanowska, D.; Gilbert, I. H. Bioorg. Med. Chem., 2005, 13, 5435-5453. link to journal abstract in pubmed link to the journal where paper was published

Biphenylquinuclidines as inhibitors of squalene synthase and growth of parasitic protozoa. Orenes Lorente, S.; Gomez, R.; Jimenez, C.; Cammerer, S.; Yardley, V.; de Luca-Fradley, K.; Croft, S. L.; Ruiz Perez, L. M.; Urbina, J.; Gonazalez Pacanowska, D.; Gilbert, I. H. Bioorg. Med. Chem., 2005 , 13, 3519-3529. link to journal abstract in pubmed link to the journal where paper was published

dUTPase as a Platform for Antimalarial Drug Design: Structural Basis for the Selectivity of a Class of Nucleoside Inhibitors. Whittingham, J. L.; Leal, I.; Nguyen, C.; Kasinathan, G.; Bell, E.; Jones, A. F.; Berry, C.; Benito, A.; Turkenburg, J. P.; Dodson, E. J.; Ruiz Perez, L. M.; Wilkinson, A. J.; Johansson, N. G.; Brun, R.; Gilbert, I. H.; Gonzalez Pacanowska, D.; Wilson, K. S. Structure, 2005, 13, 329-338. link to journal abstract in pubmed link to the journal where paper was published

Design, synthesis and evaluation of 2,4-diaminoquinazolines as inhibitors of trypanosomal and leishmanial dihydrofolate reductase. Khabnadideh, S.; Pez, D.; Musso, A.; Brun, R.; Ruiz Pérez, L. M.; González-Pacanowska, D.; Gilbert, I. H. Bioorg. Med. Chem., 2005, 13, 2637-2649. link to journal abstract in pubmed link to the journal where paper was published

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