Papers 2004

Synthesis of Analogues of Congo Red and Evaluation of Their Anti-Prion Activity. Sellarajah, S.; Lekishvili, T.; Bowring, C.; Thompsett, A. R.; Rudyk, H.; Birkett, C. R.; Brown D. R.; Gilbert, I. H. J. Med. Chem., 2004, 47, 5515-5534.  link to journal abstract in pubmed  link to the journal where paper was published

Selective inhibition of Trypanosoma brucei 6-phosphogluconate dehydrogenase by high energy intermediate and transition state analogues. Dardonville, C.; Rinaldi, E.; Barrett, M. P.; Brun, R.; Gilbert, I. H.; Hanau, S. J. Med. Chem., 2004, 47, 3427-3437.  link to journal abstract in pubmed  link to the journal where paper was published

Novel Azasterols as Potential Agents for the Treatment of Leishmaniasis and Trypanosomiasis. Orenes Lorente, S.; Rodrigues, J. C. F.; Jiménez Jiménez, C.; Joyce-Menekse, M.; Rodrigues, C.; Croft, S. L.; Yardley, V.; de Luca-Fradley, K.; Ruiz-Pérez, L. M.; Urbina, J.; de Souza, W.; González Pacanowska, D.; Gilbert, I. H. Antimicrob. Agents Chemother., 2004, 48, 2937-2950.  link to journal abstract in pubmed  link to the journal where paper was published

Design, Synthesis and Evaluation of Potential Inhibitors of HIV gp120-CD4 Interactions. Boussard, C.; Klimkait, T.; Mahmood, N.; Pritchard, M.; Gilbert, I. H. Bioorg. Med. Chem. Lett., 2004, 14, 2673-2676.  link to journal abstract in pubmed  link to the journal where paper was published

6-Phosphogluconate dehydrogenase: a target for drugs in African trypanosomes. Hanau, S.; Rinaldi, E.; Dallocchio, F.; Gilbert, I. H.; Dardonville, C.; Adams, M. J.; Gover, S.; Barrett, M. P. Curr. Med. Chem., 2004, 11 2639-2650.  link to journal abstract in pubmed  link to the journal where paper was published

Trypanocidal activity of melamine–based nitroheterocycles. Stewart, M. L.; Jimenez Bueno, G.; Baliani, A.; Klenke, B.; Brun, R.; Brock, J. M.; Gilbert, I. H.; Barrett, M. P. Antimicrob. Agents Chemother., 2004, 48, 1733-1738.  link to journal abstract in pubmed  link to the journal where paper was published

Analogues of Thiolactomycin as Potential Anti-malarial and Anti-trypanosomal Agents. Jones, S. M.; Urch, J. E.; Brun, R.; Harwood, J. L.; Berry, C.; Gilbert, I. H. Bioorg. Med. Chem., 2004, 12, 683-692.  link to journal abstract in pubmed  link to the journal where paper was published