Synthesis and testing of peptides for anti-prion activity. Sellarajah, S.; Boussard, C.; Lekishvili, T.; Brown, D. R.; Gilbert, I. H. Eur. J. Med. Chem., 2008, 43, 2418-2427.
Lessons learnt from assembling screening libraries for drug discovery for neglected diseases. Brenk, R.; Schipani, A.; James, D.; Krasowski, A.; Gilbert, I. H.; Frearson, J. A.; Wyatt, P. G. ChemMedChem, 2008, 3, 435-444.
Target assessment for antiparasitic drug discovery. Frearson, J. A.; Wyatt, P. G.; Gilbert, I. H.; Fairlamb, A. H. Trends Parasitol., 2007, 23, 589-595.
Mechanistic Insights into the Cure of Prion Disease by Novel Antiprion Compounds. Webb, S.; Lekishvili, T.; Loeschner, C.; Sellarajah, S.; Prelli, F.; Wisniewski, T.; Gilbert, I. H.; Brown, D. R. J. Virol., 2007,.81, 10729-10741.
Azasterols impair Giardia lamblia proliferation and induces encystation. Maia, C.; Attias, M.; Urbina, J. Gilbert, I.; Magaraci, F.; de Souza, W. Biochemical and Biophysical Research Communications, 2007, 363, 310-316.
Quinuclidine Derivatives as Potential Anti-parasitics. Cammerer, B. B.; Jimenez, C.; Jones, S.; Gros, L.; Orenes Lorente, S.; Rodrigues, C.; Rodrigues, J. C. F.; Caldera, A.; Ruiz-Perez, L. M.; da Souza, W.; Kasier, M.; Brun, R.; Urbina, J. A.; Gonzalez Pacanowska, D.; Gilbert, I. H. Antimicrob. Agents. Chemother., 2007, 51, 4049-4061.
Alterations on the growth and ultrastructure of Leishmania chagasi induced by squalene synthase inhibitors. Granthon, A. C.; Braga, M. V.; Rodrigues, J. C.; Cammerer, S.; Lorente, S. O.; Gilbert, I. H.; Urbina, J. A.; de Souza, W. Vet Parasitol., 2007, 146, 25-34.
Synthesis and Biological Evaluation of Phosphate Prodrugs of 4-Phospho-d-erythronohydroxamic Acid, an Inhibitor of 6-Phosphogluconate Dehydrogenase. Ruda, G. F.; Alibu, V. P.; Mitsos, C.; Bidet, O.; Kaiser, M.; Brun, R.; Barrett, M. P.; Gilbert, I. H. ChemMedChem, 2007, 2, 1169-1180.
Kinetic characterization of squalene synthase from Trypanosoma cruzi: selective inhibition by quinuclidine derivatives. Sealey-Cardona, M.; Simon Cammerer, C.; Jones, S.; Ruiz-Pérez, L. M.; Brun, R.; Gilbert, I. H.; Urbina, J. A.; González-Pacanowska, D. Antimicrob. Agents Chemother., 2007, 51, 2123-2129.
Inhibitors of Trypanosoma brucei 6-Phosphogluconate Dehydrogenase, Hanau, S.; Montin, K.; Gilbert, I. H.; Barrett, M. P.; Dallocchio, F. Current Bioactive Compounds, 2007, 3, 161-169.
Crystal structures of a bacterial 6-phosphogluconate dehydrogenase reveal aspects of specificity, mechanism and mode of inhibition by analogues of high-energy reaction intermediates. Sundaramoorthy, R.; Iulek, J.; Barrett, M. P.; Bidet, O.; Ruda, G. F.; Gilbert, I. H.; Hunter, W. N. FEBS J., 2007, 274, 275-286.