Tom & Conner’s review on Targeting Epigenetic Modulators Using PROTAC Degraders is now published in BMCL Great review article by Tom and Conner Read the full article. Authors: Thomas Webb, Conner Craigon, Alessio Ciulli* Title: Targeting Epigenetic Modulators Using PROTAC Degraders: Current Status…
Angus & Alessio’s review on E3 Ligase Substrate Specificity for Targeted Protein Degradation Authors: Angus D. Cowan, Alessio Ciulli* Title: Driving E3 Ligase Substrate Specificity for Targeted Protein Degradation: Lessons from Nature and the Laboratory Abstract Methods to direct the…
William Farnaby has been appointed as Principal Investigator within the newly formed Centre for Targeted Protein Degradation (CeTPD). Will’s research will innovate chemical approaches to discover and develop molecules that can probe new ways of addressing disease. There will be…
Xingui & Alessio’s News & Views article titled “DUB be good to me” is now published in Nat Chem Biol. Read the News & Views article on Nature Chemical Biology website. The title was inspired from Beats International’s song back in 1990…
Last year a new translational research centre was established to bolster the University of Dundee’s drug discovery position. The Centre for Targeted Protein Degradation (CeTPD) would allow Professor Alessio Ciulli and colleagues to expand their pioneering work in an area that has attracted billions…
Innovator of the Year is for any member or team within SLS that demonstrably achieved scientific, technical or commercial innovation that came to fruition in 2021. It has two categories, Best Innovation and Best Early-Stage Business Idea. The Best Early-Stage…
The group held their 1st Annual CeTPD Christmas Retreat on the 25th of November at Piperdam Leisure Resort. The evening was not only a party but also a chance to take stock of how far we’ve come this last year,…
LTDD 2021 LinkedIn lead ben post graphic, featuring A best in class method to quantify target engagement and cellular entry for PROTACs, presented by James Vasta Researchers from the University of Dundee and Promega Corporation have shown how a “three-headed…
Scientists at the University of Dundee have developed a new technology that provides a greater understanding into the biology of ‘undruggable’ diseases. Cells are composed of thousands of interacting proteins and their malfunction is a primary mechanism of disease development.…
Great collaboration with Danette Daniels’s group at Promega! Read the Open Access full article. Read the UoD News article: “Three heads are better than two in drug discovery concept“ Authors: Satomi Imaide, Kristin M. Riching, Nikolai Makukhin, Vesna Vetma, Claire Whitworth, Scott J.…