PhD studies and pre-PhD studies

PhD studies from Professor Chris Abell and pre-phd studies

PhD studies: Professor Chris Abell

19. Kerbarh, O., Ciulli, A., Chirgadze, D.Y., Blundell, T.L., Abell, C.

Nucleophile selectivity of chorismate-utilizing enzymes.

ChemBioChem 20078, 622–624


18. Ciulli, A., Chirgadze, D.Y., Smith, A.G., Blundell, T.L., Abell, C.

Crystal structure of ketopantoate reductase in a ternary complex with NADP+ and pantoate bound: substrate recognition, conformational change and cooperativity.

J. Biol. Chem. 2007282, 8487–8497


17. Ciulli, A., Lobley, C.M.C., Tuck, K.L., Smith, A.G., Blundell, T.L., Abell, C.

pH tuneable binding of 2′-phospho-ADP-ribose to ketopantoate reductase: a structural and calorimetric study.

Acta Cryst. D63 2007, 171–178


16. Ciulli, A., Williams, G., Smith, A.G., Blundell, T.L., Abell, C.

Probing hot spots at protein-ligand binding sites: a fragment-based approach using biophysical methods.

J. Med. Chem. 200649, 4992–5000

  • Highlighted twice in the Faculty of 1000 Biology Access the recommendation on F1000Prime
  • Highlighted in the Microcal Autumn 2007 Newsletter
  • Listed 13th Most-Accessed Article in Jul–Sept 2006


15. Kerbarh, O., Ciulli, A., Howard, N.I., Abell, C.

Salicylate biosynthesis: over-expression, purification and characterization of Irp9, a bifunctional salicylate synthase from Yersinia enterocolitica.

J. Bacteriol. 2005187, 5061–5066


14. Ciulli, A.,* Abell, C.

Biophysical tools to monitor enzyme-ligand interactions of enzymes involved in vitamin biosynthesis.

Biochem. Soc. Trans. 200533, 767–771


13. Lobley, C.M.C., Ciulli, A., Whitney, H.M., Williams, G., Smith, A.G., Abell, C., Blundell, T.L.

The crystal structure of Escherichia coli ketopantoate reductase with NADP+ bound.

Biochemistry 200544, 8930–8939


Pre-PhD Studies

12. Banci, L., Bertini, I., Ciulli, A., Fragai, M., Luchinat, C., Terni, B.

Expression and high yield production of the catalytic domain of matrix metalloproteinase 12 and of an active mutant with increased solubility.

J. Mol. Cat. A: Chem. 2003204-205, 401–408


11. Bashall, A., Ciulli, A., Harron, E.A., Lawson, G.T., McPartlin, M., Mosquera, M.E.G., Wright, D.S.

Effects of meta-substitution on aggregation in the cubanes [SnNR]4{R = [2-Me-5-MeOC6H3], [2,5-(MeO)2C6H3] and [3,5-(MeO)2C6H3]}.

J. Chem. Soc. Dalton Trans. 20026, 1046–1050