Author: UoD Web Team
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Our collaborative work on PROTAC structure-permeability relationships is now published in ACS Med Chem Lett. Title: Understanding and Improving the Membrane Permeability of VH032-Based PROTACs Authors: Victoria G. Klein, Chad E. Townsend, Andrea Testa, Michael Zengerle,…
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Claire and Alessio’s News & Views story on Carolyn Bertozzi’s group work on LYTACs is now published in Nature Title: Protein degraders extend their reach Authors: Claire Whitworth, Alessio Ciulli Molecules have previously been made that…
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Our collaboration with the Sapkota and Ganley Labs is now published in Cell Chemical Biology. Highlights Ligand (L)-inducible AdPROM consists of Halo conjugated to a target protein binder Target protein is degraded with HaloPROTAC in cells…
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Completion of our University of Dundee spin-off new-co Amphista therapeutics’s Series A investment announced today. Great news and congratulations to the whole team for this achievement! Read more on Twitter Related links University of Dundee Press Release:…
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Read the University of Dundee’s feature story: Collaboration with Boehringer Ingelheim: A world-changing idea: the development a completely new class of drugs with the potential to “drug the undruggable”
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Our dual Brd7/9 PROTAC degrader VZ185 is now available for free on Boehringer Ingelheim portal OpnMe.com Go on OpnMe.com to order VZ185 for free, and start your research now! Related links OpnMe entry: BRD7/BRD9 PROTAC | VZ185 University…
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Check our latest paper published in Angewandte. Closing the circle: A macrocyclic PROTAC has been designed and synthesized by adding a cyclizing linker to MZ1, a PROTAC targeting the bromodomain of the BET protein, Brd4. A…
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School of Life Science’s Professor Alessio Ciulli was amongst a selected group of world’s leading expert scientists and key opinion leaders who spoke at the Galien Forum on October 24, 2019, at the Alexandria Center in…
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Alessio and Will both spoke at the 2nd Targeted Protein Degradation Summit in Boston. Read more about the 2nd Targeted Protein Degradation Summit. The meeting was held in Boston during 22-24 October 2019
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Ciulli Lab reveals how the E3 ligase SOCS2 latches on to its protein substrates. Read full article on Nature Communications website.