Category: News
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Great work by Adam and Conner in this work collaboration with Scott Lokey’s Lab! Read the Open Access full article. Authors: Victoria G. Klein, Adam G. Bond, Conner Craigon, R. Scott Lokey*, and Alessio Ciulli* Title: Amide-to-Ester Substitution as a Strategy…
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The University of Dundee is one of the best universities in the UK for producing successful spinouts, according to a new report. Read full press release on the University of Dundee website. Related links UoD PR:…
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Our beginner’s guide to PROTACs and targeted protein degradation is now out in The Biochemist. Read the full article open access. Authors: Alessio Ciulli* and Nicole Trainor Title: A beginner’s guide to PROTACs and targeted protein…
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The expansion of an exemplary industry-academia collaboration will see the University of Dundee, in partnership with Boehringer Ingelheim, intensify its efforts to develop new medicines that target and destroy key cancer-causing proteins, which have previously been…
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New preprint: Estimating the cooperativity of PROTAC-induced ternary complexes using 19F NMR displacement assay Great work by Gugi. Read the pre-print article Authors: Guilherme Castro, Alessio Ciulli* Title: Estimating the cooperativity of PROTAC-induced ternary complexes using 19F NMR…
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Amide-to-ester substitution as a strategy for optimizing PROTAC permeability and cellular activity. Great work by Adam, Conner, and Tori Klein from Scott Lokey’s lab. Read the pre-print article. Authors: Klein, V.G., Bond, A.G, Craigon, C., Lokey,…
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A new translational research centre will bolster the University of Dundee’s world-leading position in a field that is revolutionising drug discovery, while helping to facilitate the development of high growth companies and create skilled jobs. A…
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New pre-print: VHL inhibitor binding increases intracellular level of VHL Great work by Julianty, in collaboration with Sonia Rocha Read the pre-print article Authors: Julianty Frost, Sonia Rocha*, Alessio Ciulli* Title: VHL inhibitor binding increases intracellular level of…
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Will and Manfred’s review on the present and future of PROTACs for cancer therapy is now out in Current Opinion in Pharmacology Read the full article. Authors: William Farnaby*, Manfred Koegl*, Darryl B. McConnell, Alessio Ciulli…
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Amphista Therapeutics, a University of Dundee spinout company, has announced a near-£40 million investment that will further its work to develop new drugs for a range of diseases. Amphista is a biopharmaceutical company creating first-in-class therapeutics…