Author: UoD Web Team

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The expansion of an exemplary industry-academia collaboration will see the University of Dundee, in partnership with Boehringer Ingelheim, intensify its efforts to develop new medicines that target and destroy key cancer-causing proteins, which have previously been…

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New preprint: Estimating the cooperativity of PROTAC-induced ternary complexes using 19F NMR displacement assay Great work by Gugi. Read the pre-print article Authors: Guilherme Castro, Alessio Ciulli* Title: Estimating the cooperativity of PROTAC-induced ternary complexes using 19F NMR…

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Amide-to-ester substitution as a strategy for optimizing PROTAC permeability and cellular activity. Great work by Adam, Conner, and Tori Klein from Scott Lokey’s lab. Read the pre-print article. Authors: Klein, V.G., Bond, A.G, Craigon, C., Lokey,…

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New pre-print: VHL inhibitor binding increases intracellular level of VHL Great work by Julianty, in collaboration with Sonia Rocha Read the pre-print article Authors: Julianty Frost, Sonia Rocha*, Alessio Ciulli* Title: VHL inhibitor binding increases intracellular level of…

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