An HFSP fellowship that sowed the seeds for PROTAC drug development
HFSP Matters: An HFSP fellowship that sowed the seeds for PROTAC drug development. by Alessio Ciulli In 2009, Alessio Ciulli was awarded an HFSP Short-Term Fellowship1 to support his 3-month research visit to Yale University to start a collaboration between his…
Royal Society of Chemistry award for Alessio Ciulli
Alessio Ciulli is awarded the 7th Capps Green Zomaya Award from the Royal Society of Chemistry. Dr Alessio Ciulli of the University of Dundee has been named the winner of a major award from the Royal Society of Chemistry. Dr Ciulli,…
Xavi wins Best Poster Prize
Xavi wins Best Poster Prize at the 2016 EFMC-ISMC conference in Manchester. Well done!
Alessio Ciulli awarded 2015 EFMC Prize
Alessio Ciulli is designated as the winner of the 2015 EFMC Prize for a Young Medicinal Chemist in Academia. Alessio Ciulli of the Division of Biological Chemistry and Drug Discovery has been awarded the European Federation for Medicinal Chemistry (EFMC)…
Cyclic and macrocyclic peptides as chemical tools to probe PPIs
Our review on cyclic and macrocyclic peptides as chemical tools to probe PPIs is now out in ChemMedChem. Read our Open Access article.
Triazolo-benzodiazepine chemistry to I-BET/JQ1 analogues for the bump-and-hole approach and BD2-selectivity
Our new paper on triazolo-benzodiazepine chemistry to I-BET/JQ1 analogues for the bump-and-hole approach and BD2-selectivity is now published in J. Med. Chem. You can read our open access Article ASAP. Obtain our compound “TC AC 28” (6-(1H-Indol-4-yl)-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-4-acetic acid methyl ester)…
Our Lab 2015 Away Day
Our Lab 2015 Away Day was at Braemar / Balmoral / Cairn-na-Cuimhne.
Alessio Ciulli receives 2015 ICBS Young Chemical Biologist Award
Alessio Ciulli is designated as the winner of the 2015 ICBS Young Chemical Biologist Award. Read more about the International Chemical Biology Society. Alessio was presented the award and invited to give a presentation during the special “Rising Stars in…
BRD4 intra-BET selective chemical degraders hijacking the VHL E3 ubiquitin ligase
Ciulli Lab develops super-targeted method of destroying tumour proteins. Scientists at the University of Dundee have developed a super-targeted method of destroying malevolent proteins in tumour cells, removing the threat of collateral damage to surrounding proteins. The research team led…
Crystallography of SOCS2-EloB-EloC complex by Arsenic SAD
Our new paper on crystallography of SOCS2-EloB-EloC complex by Arsenic SAD is now published in PLoS One. Read our paper.