Our new paper on triazolo-benzodiazepine chemistry to I-BET/JQ1 analogues for the bump-and-hole approach and BD2-selectivity is now published in J. Med. Chem.
Obtain our compound “TC AC 28” (6-(1H-Indol-4-yl)-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-4-acetic acid methyl ester) from the Tocris catalogue.
A one day symposium for the Scottish cryo-EM community took place on 30 November 2023 The First Scottish cryo-EM symposium attracted over 90 participants from across academia and industry. The event provided…
On Thursday 23rd November Alessio joined David McBeth, VP for Entreprise and Economic Transformation at Dundee, and colleagues from the University’s RIS and Amphista therapeutics in Leeds city centre for…
‘Trojan Horse’ chemical tool allows researchers to target ‘undruggable’ proteins University of Dundee researchers have developed a new molecule that is able to target and bind to a protein class…
The University of Dundee has today (Oct 26, 2023) celebrated the official opening of its multi-million pound Centre for Targeted Protein Degradation (CeTPD), by UK Science Minister George Freeman who…
The Ciulli Laboratory develops novel small molecules inducing targeted protein degradation and modulating protein-protein interactions. We do research on fundamental chemical biology and translate it via collaboration partnership with the…
We are excited to share our latest publication on the development of the first SOCS2 inhibitors | Just out in Nature Communications Our lab has worked relentlessly over many many years…
