2nd Targeted Protein Degradation Summit in Boston
Alessio and Will both spoke at the 2nd Targeted Protein Degradation Summit in Boston. Read more about the 2nd Targeted Protein Degradation Summit. The meeting was held in Boston during 22-24 October 2019
Structure of the E3 ligase SOCS2 with bound substrate
Ciulli Lab reveals how the E3 ligase SOCS2 latches on to its protein substrates. Read full article on Nature Communications website. Read University of Dundee press release: “Ciulli Lab reveals how the E3 ligase SOCS2 latches on to its protein…
Congratulations to Guilherme
Congratulations to Guilherme for successfully defending his PhD thesis viva today!
Will delivers a Targeted Protein Degradation Webinar with C&EN
You can view Will’s presentation during the webinar on YouTube or TOCRIS website.
New paper: Design and Characterization of SGK3-PROTAC1 an Isoform Specific SGK3 Kinase PROTAC Degrader
Congratulations to Hannah in Dario Alessi’s group for the great job on this study. Well done Andrea for the compound design and synthetic contributions to the project! Read the open access article Title: Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC…
Our review on bispecific small molecules that bring proteins together is published in Current Opinion in Chemical Biology
Well done Chiara! Read the full article. Authors: Chiara Maniaci and Alessio Ciulli* Title: Bifunctional chemical probes inducing protein-protein interactions. Abstract Inducing biomolecular interactions with synthetic molecules to impact biological function is a concept of enormous appeal. Recent years have seen…
University of Dundee and Eisai enter partnership
University of Dundee and Eisai enter partnership for cancer drug discovery using targeted protein degradation. Read the full press release from Eisai Related links Eisai PR: EISAI ENTERS INTO COLLABORATION RESEARCH AGREEMENT WITH UNIVERSITY OF DUNDEE ON TARGETED PROTEIN DEGRADATION…
XXVI National Meeting in Medicinal Chemistry (NMMC 2019)
Alessio delivers one of the plenary lectures at the XXVI National Meeting in Medicinal Chemistry (NMMC 2019) in Milan, Italy. Read more about conference in the ChemMedChem’s Editorial: “Overview of the XXVI National Meeting in Medicinal Chemistry” by Prof. Marina Carini and Prof.…
University and Boehringer Ingelheim collaborate for free access of PROTAC compounds
Order MZ1 for free today! Related Links University and Boehringer Ingelheim collaborate for free access of PROTAC compound University of Dundee and Boehringer Ingelheim collaborate for free access of PROTAC compound on opnMe.com Drug Discovery Today® features Dundee / Boehringer…
Dodgeball Tournament
The Group’s mighty team “Focaccia” won the 2019 PiCLS Dodgeball Tournament. Well done team! Congrats to Adam, Alessandra, Conner, Daniela, and Ryan. Good work guys – Graduate students rule!