Our collaborative work on PROTAC structure-permeability relationships is now published in ACS Med Chem Lett. Title: Understanding and Improving the Membrane Permeability of VH032-Based PROTACs Authors: Victoria G. Klein, Chad E. Townsend, Andrea Testa, Michael Zengerle, Chiara Maniaci, Scott J.…
Claire and Alessio’s News & Views story on Carolyn Bertozzi’s group work on LYTACs is now published in Nature Title: Protein degraders extend their reach Authors: Claire Whitworth, Alessio Ciulli Molecules have previously been made that induce protein destruction inside…
Our collaboration with the Sapkota and Ganley Labs is now published in Cell Chemical Biology. Highlights Ligand (L)-inducible AdPROM consists of Halo conjugated to a target protein binder Target protein is degraded with HaloPROTAC in cells expressing L-AdPROM construct HaloPROTAC-mediated…
Completion of our University of Dundee spin-off new-co Amphista therapeutics’s Series A investment announced today. Great news and congratulations to the whole team for this achievement! Read more on Twitter Related links University of Dundee Press Release: Funding success for University…
Read the University of Dundee’s feature story: Collaboration with Boehringer Ingelheim: A world-changing idea: the development a completely new class of drugs with the potential to “drug the undruggable”
Our dual Brd7/9 PROTAC degrader VZ185 is now available for free on Boehringer Ingelheim portal OpnMe.com Go on OpnMe.com to order VZ185 for free, and start your research now! Related links OpnMe entry: BRD7/BRD9 PROTAC | VZ185 University of Dundee and Boehringer…