Skip to content

No results

Ciulli Laboratory
About
Publications
Journal club
Positions
News
- Symposium 2024
Contact

Ciulli Laboratory
About
Publications
Journal club
Positions
News
- Symposium 2024
Contact

Molecular recognition of ternary complexes for targeted protein degradation

Category:2017
ByUoD Web Team
On20 Jan 2017

Read our review

Journal special issue: the cover

Figure 1. Comparison of binary and ternary therapeutic approaches

Figure 2. Molecular glues

Figure 3. Proteolysis-targeting chimaeras

Figure 4. Existing mindset in PROTAC design and optimization

Figure 5. PROTAC-induced ternary complexes and their biophysical properties

Figure 6. The process of PROTAC development"

Read our review

Journal special issue: the cover

Figure 1. Comparison of binary and ternary therapeutic approaches

Figure 2. Molecular glues

Figure 3. Proteolysis-targeting chimaeras

Figure 4. Existing mindset in PROTAC design and optimization

Figure 5. PROTAC-induced ternary complexes and their biophysical properties

Figure 6. The process of PROTAC development"

Previous Post First crystal structure of the VHL-EloBC-Cul2-Rbx1 multi-subunit complex

Next Post Ligandability of PHD finger domains of BAZ2A and BAZ2B

Related Articles

Refinement of the “Bump-and-Hole” Approach

20 January 2025

Molecular recognition of helical histone tail by PHD finger domains

23 March 2017

First ternary crystal structure of a PROTAC bound to to its E3 ligase VHL and Brd4 target

13 March 2017

University of Dundee
Nethergate
Dundee
Scotland, UK
DD1 4HN

Our jobs
Our events
Our stories
Contact the University
Accessibility
Modern slavery statement
Privacy

Search

Facebook YouTube Instagram

Scottish Registered Charity, No. SC015096. Copyright © 2026, University of Dundee