PhD studies from Professor Chris Abell and pre-phd studies
PhD studies: Professor Chris Abell
Refereed Papers In Primary Journals
* A.C. Corresponding Author
9. Kerbarh, O., Ciulli, A., Chirgadze, D.Y., Blundell, T.L., Abell, C.
Nucleophile selectivity of chorismate-utilizing enzymes.
8. Ciulli, A., Chirgadze, D.Y., Smith, A.G., Blundell, T.L., Abell, C.
Crystal structure of ketopantoate reductase in a ternary complex with NADP+ and pantoate bound: substrate recognition, conformational change and cooperativity.
J. Biol. Chem. 2007, 282, 8487–8497
7. Ciulli, A., Lobley, C.M.C., Tuck, K.L., Smith, A.G., Blundell, T.L., Abell, C.
pH tuneable binding of 2′-phospho-ADP-ribose to ketopantoate reductase: a structural and calorimetric study.
6. Ciulli, A., Williams, G., Smith, A.G., Blundell, T.L., Abell, C.
Probing hot spots at protein-ligand binding sites: a fragment-based approach using biophysical methods.
J. Med. Chem. 2006, 49, 4992–5000
- Highlighted twice in the Faculty of 1000 Biology
- Highlighted in the Microcal Autumn 2007 Newsletter
- Listed 13th Most-Accessed Article in Jul–Sept 2006
5. Kerbarh, O., Ciulli, A., Howard, N.I., Abell, C.
Salicylate biosynthesis: over-expression, purification and characterization of Irp9, a bifunctional salicylate synthase from Yersinia enterocolitica.
J. Bacteriol. 2005, 187, 5061–5066
4. Ciulli, A.,* Abell, C.
Biophysical tools to monitor enzyme-ligand interactions of enzymes involved in vitamin biosynthesis.
Biochem. Soc. Trans. 2005, 33, 767–771
3. Lobley, C.M.C., Ciulli, A., Whitney, H.M., Williams, G., Smith, A.G., Abell, C., Blundell, T.L.
The crystal structure of Escherichia coli ketopantoate reductase with NADP+ bound.
Biochemistry 2005, 44, 8930–8939
Pre-PhD Studies
2. Banci, L., Bertini, I., Ciulli, A., Fragai, M., Luchinat, C., Terni, B.
Expression and high yield production of the catalytic domain of matrix metalloproteinase 12 and of an active mutant with increased solubility.
J. Mol. Cat. A: Chem. 2003, 204-205, 401–408
1. Bashall, A., Ciulli, A., Harron, E.A., Lawson, G.T., McPartlin, M., Mosquera, M.E.G., Wright, D.S.
Effects of meta-substitution on aggregation in the cubanes [SnNR]4{R = [2-Me-5-MeOC6H3], [2,5-(MeO)2C6H3] and [3,5-(MeO)2C6H3]}.