Alessio and Suzanne organised the 17th EFMC Short Course on Medicinal Chemistry: Small Molecule Protein Degraders: A New Opportunity for Drug Design and Development in the Netherlands.
The three day course covered an intro to PROTACs and molecular glues from Alessio and Suzanne, Biophysical assays and structures from Chun-wa Chung (GSK), quality criteria for degrader probes and clinical aspects of small molecule protein degraders from Ingo Hartung (Merck), Medicinal chemistry optimisation from Andrea Testa (Amphista) and the importance of cellular degradation kinetics and mechanisms for development of potent therapeutic degraders from Danette Daniels (Foghorn Therapeutics).-from Suzanne
Great teaching and shared learning on protein degrader design. Kudos to everyone.