VHL inhibitor VH298 as novel chemical probe of the hypoxia signalling pathway

Our paper characterising VHL inhibitor VH298 as novel chemical probe of the hypoxia signalling pathway is now published in Nature Communications.

Read our open access article.

Featured in the UoD News websites

Access VH298 from the Chemical Probes portal.

Related Links

• Article | OPEN Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition
• Drug Discovery Today news: `Molecular commando’ identified to tackle hypoxia pathway
• New therapeutic target for diseases caused by lack of oxygen
• VH298 on the Chemical Probes Portal