Selectivity of chemical probes targeting bromodomains

Category:2016, News
ByUoD Web Team
On19 May 2016

Our review on selectivity of chemical probes targeting bromodomains is now published in Future Medicinal Chemistry.

Read our open access review without restriction .

Front page of Medicinal Chemistry screenshot for the article selectivity of chemical probes targeting bromodomains

Figure 2. Structure and molecular recognition of BET bromodomains

Figure 3.CREBBP/EP300 bromodomain

Figure 4. BRD9 bromodomain

Figure 5. BAZ2B bromodomain

Figure 7. BRPF and ATAD2 bromodomains

Figure 8. Selectivity between BD1 and BD2 BET bromodomains

Figure 9. Bump-and-hole approach

Figure 10. Dual bromodomain/kinase inhibitors.