All Sapkota Lab News on the MRC PPU website can be found here.
News Archive:
16 August 2024
Sapkota Lab Develops an Innovative Proximity-Inducing Small Molecule and Demonstrates Targeted Dephosphorylation (Link)
22 July 2023
Welcoming a new E3 ligase, KLHDC2, that can be harnessed for PROTACs. A collaborative effort with GSK, now published in Cell Chemical Biology.
2 February 2023
Luke Simpson and Luke Fulcher publish a method for targeted dephosphorylation of phospho-proteins in cells in Cell Chemical Biology.
20 October 2022
Luke and Lorraine’s paper on the impact of target protein localisation on the extent of TPD by PROTACs triggered a review by Singh and Dikic in Cell Chemical Biology.
25 September 2022
https://www.science.org/content/blog-post/degraders-here-and-there
07 January 2021
07 December 2020
https://www.ppu.mrc.ac.uk/news/congratulations-mrc-ppu-pis-gopal-sapkota-and-satpal-virdee
03 August 2020
15 July 2020
https://www.fifetoday.co.uk/health/breakthrough-dundee-university-2915194
https://www.kirkintilloch-herald.co.uk/health/breakthrough-dundee-university-2915194
https://indianexpress.com/article/lifestyle/health/university-of-dundee-cancer-kras-6510964/
15 July 2020
Scientists destroy ‘undruggable’ cancer-causing protein
15 July 2020
Luke Simpson (PhD student in Sapkota Lab) develops an inducible protein degradation technology
15 July 2020
Sascha Roth from the Sapkota lab demonstrates targeted degradation of endogenous K-RAS
15 Jan 2020
Luke Fulcher (Sapkota Lab) awarded the Howard Elder Prize
July 31, 2019
Researchers make critical cell division discovery
May 22, 2018
April 23, 2018
Congratulations to Polyxeni Bozatzi, who defended her PhD thesis. Her external examiner was Prof. Trevor Dale (Cardiff University), while her internal examiner was Prof. Grahame Hardie. Well done, Dr. Bozatzi!
March 22, 2018
PAWS1: Dundee University Press Release
PAWS1: EurekAlert News
PAWS1: News Medical Life Sciences coverage
January 15, 2018
Jun 6, 2017
SENS Antiaging research status today [Next Big Future]
May 26, 2017
Treating Diseases with a Protein Missile System [Leafscience.org]
May 11, 2017
AdPROM zeroes in on proteins [The Evening Telegraph]
May 11, 2017
Scientists develop ‘missile’ drug development technique [The Courier and Advertiser]
May 10, 2017
Sapkota Lab Describes A ‘Protein Missile’ System To Destroy Endogenous Proteins In Cells
‘Protein missile‘ raises possibility of disease breakthroughs [Phys.Org]
‘Protein missile’ raises possibility of disease breakthroughs [http://healthmedicinet.com]
Oct 26, 2016
Oct 10, 2016
The Poster Boys Of The MRC-PPU At The Annual PiCLS Symposium