Publications

– Prioritization of Molecular Targets for Antimalarial Drug Discovery

Barbara Forte, Sabine Ottilie, Andrew Plater, Brice Campo, Koen J. Dechering, Francisco Javier Gamo, Daniel E. Goldberg, Eva S. Istvan, Marcus Lee, Amanda K. Lukens, Case W. McNamara, Jacquin C. Niles, John Okombo, Charisse Flerida A. Pasaje, Miles G. Siegel, Dyann Wirth, Susan Wyllie, David A. Fidock, Beatriz Baragaña, Elizabeth A. Winzeler, and Ian H. Gilbert
 
ACS Infectious Diseases 2021 7 (10), 2764-2776

DOI: 10.1021/acsinfecdis.1c00322

– Mycobacterium tuberculosis Phe-tRNA synthetase: structural insights into tRNA recognition and aminoacylation

Karolina Michalska, Robert Jedrzejczak, Jacek Wower, Changsoo Chang, Beatriz Baragaña, Ian H Gilbert, Barbara Forte, Andrzej Joachimiak 

Nucleic Acids Research, Volume 49, Issue 9, 21 May 2021, 5351–5368                                                                                               https://doi.org/10.1093/nar/gkab272

– MalDA, Accelerating Malaria Drug Discovery

Tuo Yang, Sabine Ottilie, Eva S Istvan, Karla P Godinez-Macias, Amanda K Lukens, Beatriz Baragaña, Brice Campo, Chris Walpole, Jacquin C Niles, Kelly Chibale, Koen J Dechering , Manuel Llinás , Marcus C S Lee, Nobutaka Kato, Susan Wyllie, Case W McNamara, Francisco Javier Gamo, Jeremy Burrows, David A Fidock, Daniel E Goldberg, Ian H Gilbert, Dyann F Wirth, Elizabeth A Winzeler, Malaria Drug Accelerator Consortium.                                       

Trends Parasitol. 2021 , Volume 37, Issue 6, 493-507, June 01, 2021                                                                                                                                                       DOI: 10.1016/j.pt.2021.01.009

Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention

Robert L Summers RL, Charisse Flerida A Pasaje CFA, Joao P Pisco JP, Josefine Striepen J, Madeline R Luth MR, Krittikorn Kumpornsin K, Emma F Carpenter EF, Justin T Munro JT, De Lin , Andrew Plater A, Avinash S Punekar AS, Andrew M Shepherd AM, Sharon M Shepherd SM, Manu Vanaerschot M, James M Murithi JM, Kelly Rubiano K, Aslı Akidil A, Sabine Ottilie S, Nimisha Mittal N, A Hazel Dilmore AH, Madalyn Won M, Rebecca E K Mandt REK, Kerry McGowen K, Edward Owen E, Chris Walpole C, Manuel Llinás M, Marcus C S Lee MCS, Elizabeth A Winzeler EA, David A Fidock DA, Ian H Gilbert IH, Dyann F Wirth DF, Jacquin C Niles JC, Beatriz Baragaña B, Amanda K Lukens AK

Cell chemical biology (2021), https://doi.org/10.1016/j.chembiol.2021.07.010

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis

Beatriz BaragañaBarbara ForteRyan ChoiStephen Nakazawa Hewitt et al.