Structure Guided Drug Discovery for
Malaria and Tuberculosis
SDDC (Structure guided Drug Discovery Coalition) is an international collaboration led by the Drug Discovery Unit (DDU-Dundee) at the University of Dundee-Scotland with researchers from the University of Washington, Seattle (SSCGID-Seattle), USA, the University of Chicago (CSGID-Chicago) , USA and University of Campinas (Centre of Medicinal Chemistry-UNICAMP), Brazil. The coalition was granted $5M over the next 3 years (2Q 2024) by the Bill & Melinda Gates Foundation.
SDDC primary aim is to develop compounds to “Early Lead” status, with Proof-of-Concept in animal models of infection for Malaria and Tuberculosis
Our Approach to speed up Malaria an Tuberculosis drug discovery process
Medicinal Chemistry projects are focussed on the best disease-validated targets only.
The projects preferably have protein-small molecule structures, enabling structure-guided medicinal chemistry.
Our Collaborative Structure