{"id":696,"date":"2013-09-17T21:13:13","date_gmt":"2013-09-17T21:13:13","guid":{"rendered":"http:\/\/blog.dundee.ac.uk\/ian-gilbert\/?page_id=696"},"modified":"2013-12-20T13:14:31","modified_gmt":"2013-12-20T13:14:31","slug":"papers-2005","status":"publish","type":"page","link":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/papers-2005\/","title":{"rendered":"Papers 2005"},"content":{"rendered":"<p>Interaction of Monobenzamidine-Linked Trypanocides with the Trypanosoma brucei P2 Aminopurine Transporter, Stewart, M. L.; Boussard, C.; Brun, R.; Gilbert, I. H.; Barrett, M. P. Antimicrob. Agents Chemother., 2005, 49, 5169-5171. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16304196\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-19\" alt=\"link to journal abstract in pubmed\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/pubmed.jpg\" width=\"50\" height=\"20\" \/><\/a> <a href=\"http:\/\/aac.asm.org\/content\/49\/12\/5169.long\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-99\" alt=\"link to the journal where paper was published\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/journal.jpg\" width=\"54\" height=\"20\" \/><\/a><\/p>\n<p>Effects of Inhibitors of [Delta]24(25)-Sterol Methyl Transferase on the Ultrastructure of Epimastigotes of Trypanosoma cruzi. Braga, M. V.; Magaraci, F.; Orenes Lorente, S.; Gilbert, I. H.; de Souza, W. Microsc. Microanal., 2005, 11, 506-511. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17481329\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-19\" alt=\"link to journal abstract in pubmed\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/pubmed.jpg\" width=\"50\" height=\"20\" \/><\/a> <a href=\"http:\/\/journals.cambridge.org\/action\/displayAbstract?fromPage=online&amp;aid=351722\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-99\" alt=\"link to the journal where paper was published\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/journal.jpg\" width=\"54\" height=\"20\" \/><\/a><\/p>\n<p>Analogs of Thiolactomycin as Potential Antimalarial Agents. Jones, S. M.; Urch, J. E.; Kaiser, M.; Brun, R.; Harwood, J. L.; Berry, C.; Gilbert, I. H. J. Med. Chem.,2005, 48, 5932-5941. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16161997\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-19\" alt=\"link to journal abstract in pubmed\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/pubmed.jpg\" width=\"50\" height=\"20\" \/><\/a> <a href=\"http:\/\/pubs.acs.org\/doi\/abs\/10.1021\/jm049067d\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-99\" alt=\"link to the journal where paper was published\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/journal.jpg\" width=\"54\" height=\"20\" \/><\/a><\/p>\n<p>Deoxyuridine Triphosphate Nucleotidohydrolase as a Potential Antiparasitic Drug Target. Nguyen, C.; Kasinathan, G.; Leal-Cortijo, I.; Musso-Buendia, A.; Kaiser, M.; Brun, R.; Ruiz-P\u00e9rez, L. M.; Johansson, N. G.; Gonz\u00e1lez-Pacanowska, D.; Gilbert, I. H. J. Med. Chem., 2005, 48, 5942-5954. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16161998\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-19\" alt=\"link to journal abstract in pubmed\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/pubmed.jpg\" width=\"50\" height=\"20\" \/><\/a> <a href=\"http:\/\/pubs.acs.org\/doi\/abs\/10.1021\/jm050111e\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-99\" alt=\"link to the journal where paper was published\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/journal.jpg\" width=\"54\" height=\"20\" \/><\/a><\/p>\n<p>Design and synthesis of a series of melamine-based nitroheterocycles with activity against trypanosomatid parasites. B aliani, A.; Jimenez Bueno, G.; Stewart, M. L.; Yardley, V.; Brun, R.; Barrett, M. P.; Gilbert, I. H. J. Med. Chem., 2005, 48, 5570-5579. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16107157\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-19\" alt=\"link to journal abstract in pubmed\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/pubmed.jpg\" width=\"50\" height=\"20\" \/><\/a> <a href=\"http:\/\/pubs.acs.org\/doi\/abs\/10.1021\/jm050177%2B\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-99\" alt=\"link to the journal where paper was published\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/journal.jpg\" width=\"54\" height=\"20\" \/><\/a><\/p>\n<p>Preparation of Transition-State Analogues of Sterol 24-Methyl Transferase as Potential Anti-Parasitics. Orenes Lorente, S.; Jimenez Jimenez, C.; Gros, L.; Yardley, V.; de Luca-Fradley, K.; Croft, S. L.; Urbina, J. A.; Ruiz-Perez, L. M.; Gonzalez Pacanowska, D.; Gilbert, I. H. Bioorg. Med. Chem., 2005, 13, 5435-5453. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16046134\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-19\" alt=\"link to journal abstract in pubmed\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/pubmed.jpg\" width=\"50\" height=\"20\" \/><\/a> <a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0968089605005274\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-99\" alt=\"link to the journal where paper was published\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/journal.jpg\" width=\"54\" height=\"20\" \/><\/a><\/p>\n<p>Biphenylquinuclidines as inhibitors of squalene synthase and growth of parasitic protozoa. Orenes Lorente, S.; Gomez, R.; Jimenez, C.; Cammerer, S.; Yardley, V.; de Luca-Fradley, K.; Croft, S. L.; Ruiz Perez, L. M.; Urbina, J.; Gonazalez Pacanowska, D.; Gilbert, I. H. Bioorg. Med. Chem., 2005 , 13, 3519-3529. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15848765\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-19\" alt=\"link to journal abstract in pubmed\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/pubmed.jpg\" width=\"50\" height=\"20\" \/><\/a> <a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0968089605001951\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-99\" alt=\"link to the journal where paper was published\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/journal.jpg\" width=\"54\" height=\"20\" \/><\/a><\/p>\n<p>dUTPase as a Platform for Antimalarial Drug Design: Structural Basis for the Selectivity of a Class of Nucleoside Inhibitors. Whittingham, J. L.; Leal, I.; Nguyen, C.; Kasinathan, G.; Bell, E.; Jones, A. F.; Berry, C.; Benito, A.; Turkenburg, J. P.; Dodson, E. J.; Ruiz Perez, L. M.; Wilkinson, A. J.; Johansson, N. G.; Brun, R.; Gilbert, I. H.; Gonzalez Pacanowska, D.; Wilson, K. S. Structure, 2005, 13, 329-338. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15698576\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-19\" alt=\"link to journal abstract in pubmed\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/pubmed.jpg\" width=\"50\" height=\"20\" \/><\/a> <a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0969212605000328\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-99\" alt=\"link to the journal where paper was published\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/journal.jpg\" width=\"54\" height=\"20\" \/><\/a><\/p>\n<p>Design, synthesis and evaluation of 2,4-diaminoquinazolines as inhibitors of trypanosomal and leishmanial dihydrofolate reductase. Khabnadideh, S.; Pez, D.; Musso, A.; Brun, R.; Ruiz P\u00e9rez, L. M.; Gonz\u00e1lez-Pacanowska, D.; Gilbert, I. H. Bioorg. Med. Chem., 2005, 13, 2637-2649. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15755663\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-19\" alt=\"link to journal abstract in pubmed\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/pubmed.jpg\" width=\"50\" height=\"20\" \/><\/a> <a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0968089605000519\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-99\" alt=\"link to the journal where paper was published\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/journal.jpg\" width=\"54\" height=\"20\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Interaction of Monobenzamidine-Linked Trypanocides with the Trypanosoma brucei P2 Aminopurine Transporter, Stewart, M. L.; Boussard, C.; Brun, R.; Gilbert, I. H.; Barrett, M. P. Antimicrob. Agents Chemother., 2005, 49, 5169-5171. Effects of Inhibitors of [Delta]24(25)-Sterol Methyl Transferase on the Ultrastructure of Epimastigotes of Trypanosoma cruzi. Braga, M. V.; Magaraci, F.; Orenes Lorente, S.; Gilbert, I. [&hellip;]<\/p>\n","protected":false},"author":8,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"full-width-page.php","meta":{"footnotes":""},"class_list":["post-696","page","type-page","status-publish","hentry"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/pages\/696","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/comments?post=696"}],"version-history":[{"count":1,"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/pages\/696\/revisions"}],"predecessor-version":[{"id":1015,"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/pages\/696\/revisions\/1015"}],"wp:attachment":[{"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/media?parent=696"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}