{"id":693,"date":"2013-09-17T21:11:15","date_gmt":"2013-09-17T21:11:15","guid":{"rendered":"http:\/\/blog.dundee.ac.uk\/ian-gilbert\/?page_id=693"},"modified":"2013-12-20T13:14:57","modified_gmt":"2013-12-20T13:14:57","slug":"papers-2007","status":"publish","type":"page","link":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/papers-2007\/","title":{"rendered":"Papers 2007"},"content":{"rendered":"<p>Synthesis and testing of peptides for anti-prion activity. Sellarajah, S.; Boussard, C.; Lekishvili, T.; Brown, D. R.; Gilbert, I. H. Eur. J. Med. Chem., 2008, 43, 2418-2427. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18355947\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-19\" alt=\"link to journal abstract in pubmed\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/pubmed.jpg\" width=\"50\" height=\"20\" \/><\/a> <a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0223523408000603\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-99\" alt=\"link to the journal where paper was published\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/journal.jpg\" width=\"54\" height=\"20\" \/><\/a><\/p>\n<p>Lessons learnt from assembling screening libraries for drug discovery for neglected diseases. Brenk, R.; Schipani, A.; James, D.; Krasowski, A.; Gilbert, I. H.; Frearson, J. A.; Wyatt, P. G. ChemMedChem, 2008, 3, 435-444. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18064617\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-19\" alt=\"link to journal abstract in pubmed\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/pubmed.jpg\" width=\"50\" height=\"20\" \/><\/a> <a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cmdc.200700139\/abstract\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-99\" alt=\"link to the journal where paper was published\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/journal.jpg\" width=\"54\" height=\"20\" \/><\/a><\/p>\n<p>Target assessment for antiparasitic drug discovery. Frearson, J. A.; Wyatt, P. G.; Gilbert, I. H.; Fairlamb, A. H. Trends Parasitol., 2007, 23, 589-595. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17962072\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-19\" alt=\"link to journal abstract in pubmed\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/pubmed.jpg\" width=\"50\" height=\"20\" \/><\/a> <a href=\"http:\/\/www.cell.com\/trends\/parasitology\/\/retrieve\/pii\/S147149220700253X?_returnURL=http:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S147149220700253X?showall=true\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-99\" alt=\"link to the journal where paper was published\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/journal.jpg\" width=\"54\" height=\"20\" \/><\/a><\/p>\n<p>Mechanistic Insights into the Cure of Prion Disease by Novel Antiprion Compounds. Webb, S.; Lekishvili, T.; Loeschner, C.; Sellarajah, S.; Prelli, F.; Wisniewski, T.; Gilbert, I. H.; Brown, D. R. J. Virol., 2007,.81, 10729-10741. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17652397\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-19\" alt=\"link to journal abstract in pubmed\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/pubmed.jpg\" width=\"50\" height=\"20\" \/><\/a> <a href=\"http:\/\/jvi.asm.org\/content\/81\/19\/10729.long\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-99\" alt=\"link to the journal where paper was published\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/journal.jpg\" width=\"54\" height=\"20\" \/><\/a><\/p>\n<p>Azasterols impair Giardia lamblia proliferation and induces encystation. Maia, C.; Attias, M.; Urbina, J. Gilbert, I.; Magaraci, F.; de Souza, W. Biochemical and Biophysical Research Communications, 2007, 363, 310-316. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17870055\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-19\" alt=\"link to journal abstract in pubmed\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/pubmed.jpg\" width=\"50\" height=\"20\" \/><\/a> <a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0006291X07018803\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-99\" alt=\"link to the journal where paper was published\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/journal.jpg\" width=\"54\" height=\"20\" \/><\/a><\/p>\n<p>Quinuclidine Derivatives as Potential Anti-parasitics. Cammerer, B. B.; Jimenez, C.; Jones, S.; Gros, L.; Orenes Lorente, S.; Rodrigues, C.; Rodrigues, J. C. F.; Caldera, A.; Ruiz-Perez, L. M.; da Souza, W.; Kasier, M.; Brun, R.; Urbina, J. A.; Gonzalez Pacanowska, D.; Gilbert, I. H. Antimicrob. Agents. Chemother., 2007, 51, 4049-4061. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17709461\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-19\" alt=\"link to journal abstract in pubmed\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/pubmed.jpg\" width=\"50\" height=\"20\" \/><\/a> <a href=\"http:\/\/aac.asm.org\/content\/51\/11\/4049.long\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-99\" alt=\"link to the journal where paper was published\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/journal.jpg\" width=\"54\" height=\"20\" \/><\/a><\/p>\n<p>Alterations on the growth and ultrastructure of Leishmania chagasi induced by squalene synthase inhibitors. Granthon, A. C.; Braga, M. V.; Rodrigues, J. C.; Cammerer, S.; Lorente, S. O.; Gilbert, I. H.; Urbina, J. A.; de Souza, W. Vet Parasitol., 2007, 146, 25-34. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17367936\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-19\" alt=\"link to journal abstract in pubmed\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/pubmed.jpg\" width=\"50\" height=\"20\" \/><\/a> <a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0304401707000076\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-99\" alt=\"link to the journal where paper was published\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/journal.jpg\" width=\"54\" height=\"20\" \/><\/a><\/p>\n<p>Synthesis and Biological Evaluation of Phosphate Prodrugs of 4-Phospho-d-erythronohydroxamic Acid, an Inhibitor of 6-Phosphogluconate Dehydrogenase. Ruda, G. F.; Alibu, V. P.; Mitsos, C.; Bidet, O.; Kaiser, M.; Brun, R.; Barrett, M. P.; Gilbert, I. H. ChemMedChem, 2007, 2, 1169-1180. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17615587\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-19\" alt=\"link to journal abstract in pubmed\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/pubmed.jpg\" width=\"50\" height=\"20\" \/><\/a> <a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cmdc.200700040\/abstract\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-99\" alt=\"link to the journal where paper was published\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/journal.jpg\" width=\"54\" height=\"20\" \/><\/a><\/p>\n<p>Kinetic characterization of squalene synthase from Trypanosoma cruzi: selective inhibition by quinuclidine derivatives. Sealey-Cardona, M.; Simon Cammerer, C.; Jones, S.; Ruiz-P\u00e9rez, L. M.; Brun, R.; Gilbert, I. H.; Urbina, J. A.; Gonz\u00e1lez-Pacanowska, D. Antimicrob. Agents Chemother., 2007, 51, 2123-2129. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17371809\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-19\" alt=\"link to journal abstract in pubmed\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/pubmed.jpg\" width=\"50\" height=\"20\" \/><\/a> <a href=\"http:\/\/aac.asm.org\/content\/51\/6\/2123.long\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-99\" alt=\"link to the journal where paper was published\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/journal.jpg\" width=\"54\" height=\"20\" \/><\/a><\/p>\n<p>Inhibitors of Trypanosoma brucei 6-Phosphogluconate Dehydrogenase, Hanau, S.; Montin, K.; Gilbert, I. H.; Barrett, M. P.; Dallocchio, F. Current Bioactive Compounds, 2007, 3, 161-169. <a href=\"http:\/\/eurekaselect.com\/59800\/article\/inhibitors-trypanosoma-brucei-6-phosphogluconate-dehydrogenase\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone\" alt=\"link to the journal where paper was published\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/journal.jpg\" width=\"54\" height=\"20\" \/><\/a><\/p>\n<p>Crystal structures of a bacterial 6-phosphogluconate dehydrogenase reveal aspects of specificity, mechanism and mode of inhibition by analogues of high-energy reaction intermediates. Sundaramoorthy, R.; Iulek, J.; Barrett, M. P.; Bidet, O.; Ruda, G. F.; Gilbert, I. H.;\u00a0 Hunter, W. N. FEBS J., 2007, 274, 275-286. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17222187\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-19\" alt=\"link to journal abstract in pubmed\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/pubmed.jpg\" width=\"50\" height=\"20\" \/><\/a> <a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1742-4658.2006.05585.x\/abstract\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-99\" alt=\"link to the journal where paper was published\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/journal.jpg\" width=\"54\" height=\"20\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Synthesis and testing of peptides for anti-prion activity. Sellarajah, S.; Boussard, C.; Lekishvili, T.; Brown, D. R.; Gilbert, I. H. Eur. J. Med. Chem., 2008, 43, 2418-2427. Lessons learnt from assembling screening libraries for drug discovery for neglected diseases. Brenk, R.; Schipani, A.; James, D.; Krasowski, A.; Gilbert, I. H.; Frearson, J. A.; Wyatt, P. [&hellip;]<\/p>\n","protected":false},"author":8,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"full-width-page.php","meta":{"footnotes":""},"class_list":["post-693","page","type-page","status-publish","hentry"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/pages\/693","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/comments?post=693"}],"version-history":[{"count":1,"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/pages\/693\/revisions"}],"predecessor-version":[{"id":1017,"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/pages\/693\/revisions\/1017"}],"wp:attachment":[{"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/media?parent=693"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}