{"id":56,"date":"2013-09-05T16:50:38","date_gmt":"2013-09-05T16:50:38","guid":{"rendered":"http:\/\/blog.dundee.ac.uk\/ian-gilbert\/?page_id=56"},"modified":"2026-03-16T16:40:21","modified_gmt":"2026-03-16T16:40:21","slug":"key-publications","status":"publish","type":"page","link":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/key-publications\/","title":{"rendered":"Key Publications"},"content":{"rendered":"\n<figure class=\"wp-block-image alignleft\"><a href=\"http:\/\/scholar.google.co.uk\/citations?user=ucHYISkAAAAJ&amp;hl=en\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"92\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/google_scholar-IHG-300x92.jpg\" alt=\"Ian Gilbert pulbications in Google scholar\" class=\"wp-image-1078\" title=\"http:\/\/scholar.google.co.uk\/citations?user=ucHYISkAAAAJ&amp;hl=en\" srcset=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/google_scholar-IHG-300x92.jpg 300w, https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/google_scholar-IHG-150x46.jpg 150w, https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/google_scholar-IHG.jpg 318w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<p>&nbsp;<\/p>\n\n\n\n<p>&nbsp;<\/p>\n\n\n\n<p>&nbsp;<\/p>\n\n\n\n<figure class=\"wp-block-image alignright\"><a href=\"https:\/\/www.nature.com\/articles\/s41586-018-0356-z\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"60\" height=\"16\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/nature60.png\" alt=\"nature60\" class=\"wp-image-919\"\/><\/a><\/figure>\n\n\n\n<p><a href=\"https:\/\/www.nature.com\/articles\/s41586-018-0356-z\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #808000;\">Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis<\/span><\/a><br \/><strong><em>Nature<\/em>, 2018<\/strong>, 560 192-197 <\/p>\n\n\n\n<figure class=\"wp-block-image alignright\"><a href=\"https:\/\/www.nature.com\/articles\/s41586-018-0327-4\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"60\" height=\"16\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/nature60.png\" alt=\"nature60\" class=\"wp-image-919\"\/><\/a><\/figure>\n\n\n\n<p><a href=\"https:\/\/www.nature.com\/articles\/s41586-018-0327-4\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #808000;\">Challenges and recent progress in drug discovery for tropical diseases<\/span><\/a><br \/><strong><em>Nature<\/em>, 2015<\/strong>, 559, 498-506 <\/p>\n\n\n\n<figure class=\"wp-block-image alignright\"><a href=\"http:\/\/www.nature.com\/nature\/journal\/v522\/n7556\/full\/nature14451.html\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"60\" height=\"16\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/nature60.png\" alt=\"nature60\" class=\"wp-image-919\"\/><\/a><\/figure>\n\n\n\n<p><a href=\"http:\/\/www.nature.com\/nature\/journal\/v522\/n7556\/full\/nature14451.html\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #808000;\">A novel multiple-stage antimalarial agent that inhibits protein synthesis<\/span><\/a><br \/><strong><em>Nature<\/em>, 2015<\/strong>, 522, 315-320 <\/p>\n\n\n\n<figure class=\"wp-block-image alignright\"><a href=\"http:\/\/pubs.acs.org\/doi\/abs\/10.1021\/jm500809c\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"150\" height=\"87\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/JMedChem-150x87.png\" alt=\"JMedChem\" class=\"wp-image-1247\" srcset=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/JMedChem-150x87.png 150w, https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/JMedChem-300x175.png 300w, https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/JMedChem-100x58.png 100w, https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/JMedChem-200x116.png 200w, https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/JMedChem.png 428w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/a><\/figure>\n\n\n\n<p class=\"has-text-align-left\"><span style=\"color: #808000;\"><a href=\"http:\/\/pubs.acs.org\/doi\/abs\/10.1021\/jm500809c\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #808000;\">Lead Optimization of a Pyrazole Sulfonamide Series of Trypanosoma brucei N-Myristoyltransferase Inhibitors: Idenification and Evaluation of CNS Penetrant Compounds as Potential Treatments for Stage 2 Human African Trypanosomiasis<\/span><\/a><\/span><br \/><em><strong>J<\/strong> <strong>Med. Chem, 2014,<\/strong> <\/em>57, 9855-9869 <\/p>\n\n\n\n<p>&nbsp;<\/p>\n\n\n\n<figure class=\"wp-block-image alignright\"><a href=\"http:\/\/www.nature.com\/nature\/journal\/v492\/n7428\/full\/nature11691.html\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"60\" height=\"16\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/nature60.png\" alt=\"nature60\" class=\"wp-image-919\"\/><\/a><\/figure>\n\n\n\n<p class=\"has-text-align-left\"><a href=\"http:\/\/www.nature.com\/nature\/journal\/v492\/n7428\/full\/nature11691.html\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #808000;\"><span style=\"color: #808000;\">Automated design of ligands to polypharmacological profiles<\/span><\/span><\/a><br \/><strong><em>Nature<\/em>, 2012<\/strong>, 492, 215-22 <\/p>\n\n\n\n<figure class=\"wp-block-image alignright\"><a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cmdc.201100420\/abstract\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"60\" height=\"15\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/ChemMedChem-60.png\" alt=\"ChemMedChem-60\" class=\"wp-image-921\"\/><\/a><\/figure>\n\n\n\n<p class=\"has-text-align-left\"><span style=\"color: #808000;\"><a title=\"Ian Gilbert ChemMedChem 2012\" href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cmdc.201100420\/abstract\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #808000;\">Design, Synthesis and Biological Evaluation of Trypanosoma brucei Trypanothione Synthetase Inhibitors<\/span><\/a><\/span><br \/><strong><em>ChemMedChem<\/em>,<\/strong> <strong>2012<\/strong>, 7, 95-106&nbsp; <\/p>\n\n\n\n<figure class=\"wp-block-image alignright\"><a href=\"http:\/\/www.nature.com\/nature\/journal\/v464\/n7289\/full\/nature08893.html\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"60\" height=\"16\" src=\"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-content\/uploads\/sites\/4\/2013\/09\/nature60.png\" alt=\"nature60\" class=\"wp-image-919\"\/><\/a><\/figure>\n\n\n\n<p class=\"has-text-align-left\"><a href=\"http:\/\/www.nature.com\/nature\/journal\/v464\/n7289\/full\/nature08893.html\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #808000;\"><span style=\"color: #808000;\">N-myristoyltransferase inhibitors as new leads to treat sleeping sickness<\/span><\/span><\/a><br \/><strong><em>Nature<\/em><\/strong>, <strong>2010,<\/strong> 464, 728-732&nbsp; <\/p>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; &nbsp; &nbsp; Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasisNature, 2018, 560 192-197 Challenges and recent progress in drug discovery for tropical diseasesNature, 2015, 559, 498-506 A novel multiple-stage antimalarial agent that inhibits protein synthesisNature, 2015, 522, 315-320 Lead Optimization of a Pyrazole Sulfonamide Series of Trypanosoma brucei N-Myristoyltransferase Inhibitors: Idenification and [&hellip;]<\/p>\n","protected":false},"author":8,"featured_media":0,"parent":0,"menu_order":4,"comment_status":"closed","ping_status":"closed","template":"full-width-page.php","meta":{"footnotes":""},"class_list":["post-56","page","type-page","status-publish","hentry"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/pages\/56","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/comments?post=56"}],"version-history":[{"count":66,"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/pages\/56\/revisions"}],"predecessor-version":[{"id":1803,"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/pages\/56\/revisions\/1803"}],"wp:attachment":[{"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/media?parent=56"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}