{"id":54,"date":"2013-09-05T16:48:22","date_gmt":"2013-09-05T16:48:22","guid":{"rendered":"http:\/\/blog.dundee.ac.uk\/ian-gilbert\/?page_id=54"},"modified":"2015-02-16T08:51:03","modified_gmt":"2015-02-16T08:51:03","slug":"papers2011","status":"publish","type":"page","link":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/papers2011\/","title":{"rendered":"Papers 2011"},"content":{"rendered":"

Investigation of copper(II) tetrafluoroborate catalysed epoxide opening. Capes, A. S.; Crossman, A. T.; Webster, L. A.; Ferguson, M. A. J.; Gilbert, I. H. Tetrahedron Lett. 2011, 52, 7091-7094.\u00a0\u00a0 \"pubmed\"<\/a> \"journal\"<\/a><\/p>\n

Identification of Inhibitors of the Leishmania cdc-Related Protein Kinase CRK3. Cleghorn, L. A. T.; Woodland, A.; Collie, I. T.; Torrie, L. S.; Norcross, N.; Luksch, T.; Mpamhanga, C.; Walker, R. G.; Mottram, J. C.; Brenk, R.; Frearson, J. A.; Gilbert, I. H.; Wyatt, P. G. ChemMedChem, 2011, 6, 2214-2224.\u00a0\u00a0 \"pubmed\"<\/a> \"journal\"<\/a><\/p>\n

Optimisation of the anti-Trypanosoma brucei activity of the opioid agonist U50488. Smith, V. C.; Cleghorn, L. A. T.; Woodland, A.; Spinks, D.; Hallyburton, I.; Collie, I. T.; Mok, N. Y.; Norval, S.; Brenk, R.; Fairlamb, A. H.; Frearson, J. A.; Read, K. D.; Gilbert, I. H.; Wyatt, P. G. ChemMedChem, 2011, 6, 1832-1840.\u00a0\u00a0 \"pubmed\"<\/a> \"journal\"<\/a><\/p>\n

Dihydroquinazolines as a Novel Class of Trypanosoma brucei Trypanothione Reductase Inhibitors: Discovery, Synthesis and Characterization of their Binding Mode by Protein Crystallography. Patterson, S.; Alphey, M. S.; Jones, D. C.; Shanks, E. J.; Street, I. P.; Frearson, J. A.; Wyatt, P. G.; Gilbert, I. H.; Fairlamb, A. H. J. Med. Chem., 2011, 54, 6514-6530.\u00a0\u00a0 \"pubmed\"<\/a> \"journal\"<\/a><\/p>\n

Design, Synthesis and Evaluation of 5\u2019-Diphenyl Nucleoside Analogues as Inhibitors of the Plasmodium falciparum dUTPase. Hampton, S. E.; Baragana, B.; Schipani, A.; Bosch-Navarrete, C.; Musso-Buendia, J. A.; Recio, E.; Kaiser, M.; Whittingham, J. L.; Roberts, S. M.; Shevtsov, M.; Brannigan, J. A.; Kahnberg, P.; Brun, R.; Wilson, K. S.; Gonzalez-Pacanowska, D.; Johansson, N. G.; Gilbert, I. H. ChemMedChem, 2011, 6, 1816-1831.\u00a0\u00a0 \"pubmed\"<\/a> \"journal\"<\/a><\/p>\n

Site-directed mutagenesis provides insights into the selective binding of trityl derivatives to Plasmodium falciparum dUTPase. Recio, E.; Musso-Buendia, A.; Vidal, A. E.; Ruda, G. F.; Kasinathan, G.; Nguyen, C.; Ruiz-Perez, L. M.; Gilbert, I. H.; Gonzalez-Pacanowska, D. Eur. J. Med. Chem., 2011, 46, 3309-3314.\u00a0\u00a0 \"pubmed\"<\/a> \"journal\"<\/a><\/p>\n

Synthetic arylquinuclidine derivatives exhibit antifungal activity against Candida albicans, Candida tropicalis and Candida parapsilopsis, Ishida, K.; Rodgrigues, J. C. F.; Cammerer, S.; Urbina, J. A.; Gilbert, I. H.; de Souza, W.; Rozental, S. Annals of Clinical Microbiology and Antimicrobials, 2011, 10, 3.\u00a0\u00a0 \"pubmed\"<\/a> \"journal\"<\/a><\/p>\n

Finding new hits in neglected disease projects: target or phenotypic based screening? Gilbert, I. H.; Leroy, D.; Frearson, J. A. Curr. Top. Med. Chem., 2011, 11, 1284-1291.\u00a0\u00a0 \"pubmed\"<\/a> \"journal\"<\/a><\/p>\n

Target validation: linking target and chemical properties to desired product profiles. Wyatt, P. G.; Gilbert, I. H.; Read, K. D.; Fairlamb, A. H. Curr. Top. Med. Chem., 2011, 11, 1275-1283.\u00a0\u00a0 \"pubmed\"<\/a> \"journal\"<\/a><\/p>\n

Beta-Branched Acyclic Nucleoside Analogues as Inhibitors of Plasmodium falciparum dUTPase. Baragana, B.; McCarthy, O.; Sanchez, P.; Bosch-Navarrete, C.; Kaiser, M.; Brun, M.; Whittingham, J. L.; Roberts, S.; Zhou, X.-X.; Wilson, K. S.; Johansson, N. G.; Gonzalez-Pacanowska, D.; Gilbert, I. H. Bioorg. Med. Chem., 2011, 19, 2378-2391.\u00a0\u00a0 \"pubmed\"<\/a> \"journal\"<\/a><\/p>\n

Modified 5\u2019-Trityl Nucleosides as Inhibitors of Plasmodium falciparum dUTPase. Ruda, G. F.; Nguyen, C.; Ziemkowski, P.; Felczak, K.; Kasinathan, G.; Musso-Buendia, A.; Sund, C.; Zhou, X. X.; Kaiser, M.; Ruiz-Perez, L.-M.; Brun, R.; Kulikowski, T.; Johansson, N. G.; Gonzalez-Pacanowska, D.; Gilbert, I. H. ChemMedChem, 2011, 6, 309-320.\u00a0\u00a0 \"pubmed\"<\/a> \"journal\"<\/a><\/p>\n

Design, Synthesis and Biological Evaluation of Novel Inhibitors of Trypanosoma brucei Pteridine Reductase 1. Spinks, D.; Ong, H. B.; Mpamhange, C. P.; Shanks, E. J.; Robinson, D. A.; Collie, I. T.; Read, K. D.; Frearson, J. A.; Wyatt, P. G.; Brenk, R.; Fairlamb, A. H.; Gilbert, I. H. ChemMedChem, 2011, 6, 302-308.\u00a0\u00a0 \"pubmed\"<\/a> \"journal\"<\/a><\/p>\n

Evaluation of three novel azasterols against Toxoplasma gondii. Martins-Duarte, E. S.; Lemgruber, L.; Orenes Lorente, S.; Gros, L.; Magaraci, F.; Gilbert, I. H.; de Souza, W.; Vommaro, R. C. Vet. Parasitol. 2011, 177, 157-161.\u00a0\u00a0 \"pubmed\"<\/a> \"journal\"<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Investigation of copper(II) tetrafluoroborate catalysed epoxide opening. Capes, A. S.; Crossman, A. T.; Webster, L. A.; Ferguson, M. A. J.; Gilbert, I. H. Tetrahedron Lett. 2011, 52, 7091-7094.\u00a0\u00a0 Identification of Inhibitors of the Leishmania cdc-Related Protein Kinase CRK3. Cleghorn, L. A. T.; Woodland, A.; Collie, I. T.; Torrie, L. S.; Norcross, N.; Luksch, T.; Mpamhanga, […]<\/p>\n","protected":false},"author":8,"featured_media":0,"parent":0,"menu_order":3,"comment_status":"closed","ping_status":"closed","template":"full-width-page.php","meta":{"footnotes":""},"class_list":["post-54","page","type-page","status-publish","hentry"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/pages\/54","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/comments?post=54"}],"version-history":[{"count":1,"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/pages\/54\/revisions"}],"predecessor-version":[{"id":1023,"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/pages\/54\/revisions\/1023"}],"wp:attachment":[{"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/media?parent=54"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}