{"id":1575,"date":"2018-08-20T07:14:13","date_gmt":"2018-08-20T07:14:13","guid":{"rendered":"http:\/\/sites.dundee.ac.uk\/ian-gilbert\/?page_id=1575"},"modified":"2018-08-20T10:28:15","modified_gmt":"2018-08-20T10:28:15","slug":"papers2016","status":"publish","type":"page","link":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/papers2016\/","title":{"rendered":"Papers 2016"},"content":{"rendered":"<p><a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jmedchem.6b00723\" target=\"_blank\" rel=\"noopener\">Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy<\/a>. Baraga\u00f1a, B.; Norcross, N. R.; Wilson, C.; Porzelle, A.; Hallyburton, I.; Grimaldi, R.; Osuna-Cabello, M.; Norval, S.; Riley, J.; Stojanovski, L.; Simeons, F. R., Wyatt, P. G.; Delves, M. J.; Meister, S.; Duffy, S.; Avery, V. M.; Winzeler, E. A.; Sinden, R. E.; Wittlin, S.; Frearson, J. A.; Gray, D. W.; Fairlamb, A. H.; Waterson, D.; Campbell, S. F.; Willis, P.; Read, K. D.; Gilbert, I. H. <em>J. Med. Chem., <\/em>2016, <em>59<\/em>, 9672-9685. PMCID: PMC5108032<\/p>\n<p><a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jmedchem.6b00028\" target=\"_blank\" rel=\"noopener\">Trisubstituted Pyrimidines as Efficacious and Fast-Acting Antimalarials<\/a>. Norcross, N. R.; Baraga\u00f1a, B.; Wilson, C.; Hallyburton, I.; Osuna-Cabello, M.; Norval, S.; Riley, J.; Stojanovski, L.; Simeons, F. R.; Porzelle, A.; Grimaldi, R.; Wittlin, S.; Duffy, S.; Avery, V. M.; Meister, S.; Sanz, L.; Jim\u00e9nez-D\u00eda, B.; Angulo-Barturen, I.; Ferrer, S.; Mart\u00ednez, M. S.; Gamo, F. J.; Frearson, J. A.; Gray, D. W.; Fairlamb, A. H.; Winzeler, E. A.; Waterson, D.; Campbell, S. F.; Willis, P.; Read, K. D.; Gilbert, I. H. <em>J Med Chem<\/em>., 2016, <em>59<\/em>, 6101-6120. PMCID: PMC4947981<\/p>\n<p><a href=\"http:\/\/journals.plos.org\/plosntds\/article?id=10.1371\/journal.pntd.0004540\" target=\"_blank\" rel=\"noopener\">Validation of N-myristoyltransferase as Potential Chemotherapeutic Target in Mammal-Dwelling Stages of Trypanosoma cruzi<\/a>. Herrera, L. J.; Brand, S.; Santos, A.; Nohara, L. L.; Harrison, J.; Norcross, N. R.; Thompson, S.; Smith, V.; Lema, C.; Varela-Ramirez, A.; Gilbert, I. H.; Almeida, I. C.; Maldonado, R. A. <em>PLoS Negl Trop Dis<\/em>. 2016, <em>10<\/em>, e0004540.<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy. Baraga\u00f1a, B.; Norcross, N. R.; Wilson, C.; Porzelle, A.; Hallyburton, I.; Grimaldi, R.; Osuna-Cabello, M.; Norval, S.; Riley, J.; Stojanovski, L.; Simeons, F. R., Wyatt, P. G.; Delves, M. J.; Meister, S.; Duffy, S.; Avery, V. [&hellip;]<\/p>\n","protected":false},"author":8,"featured_media":0,"parent":0,"menu_order":1,"comment_status":"closed","ping_status":"closed","template":"full-width-page.php","meta":{"footnotes":""},"class_list":["post-1575","page","type-page","status-publish","hentry"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/pages\/1575","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/comments?post=1575"}],"version-history":[{"count":3,"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/pages\/1575\/revisions"}],"predecessor-version":[{"id":1597,"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/pages\/1575\/revisions\/1597"}],"wp:attachment":[{"href":"https:\/\/sites.dundee.ac.uk\/ian-gilbert\/wp-json\/wp\/v2\/media?parent=1575"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}