{"id":2692,"date":"2015-06-29T13:13:00","date_gmt":"2015-06-29T12:13:00","guid":{"rendered":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/?p=2692"},"modified":"2026-01-26T16:28:05","modified_gmt":"2026-01-26T16:28:05","slug":"crystallography-of-socs2-elob-eloc-complex-by-arsenic-sad","status":"publish","type":"post","link":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/2015\/06\/29\/crystallography-of-socs2-elob-eloc-complex-by-arsenic-sad\/","title":{"rendered":"Crystallography of SOCS2-EloB-EloC complex by Arsenic SAD\u00a0"},"content":{"rendered":"<p>Our new paper on crystallography of SOCS2-EloB-EloC complex by Arsenic SAD is now published in PLoS One.<\/p>\n<p><a href=\"http:\/\/dx.doi.org\/10.1371\/journal.pone.0131218\">Read our paper<\/a>.<\/p>\n<div id='gallery-1' class='gallery galleryid-2692 gallery-columns-3 gallery-size-large'><figure class='gallery-item'>\n\t\t\t<div class='gallery-icon landscape'>\n\t\t\t\t<a href='https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-content\/uploads\/sites\/233\/2024\/01\/crystallography-socs2-Figure-1.png'><img loading=\"lazy\" decoding=\"async\" width=\"789\" height=\"591\" src=\"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-content\/uploads\/sites\/233\/2024\/01\/crystallography-socs2-Figure-1.png\" class=\"attachment-large size-large\" alt=\"Fig 1. Crystals of the SOCS2:EloC:EloB complex grown after 7 d\" srcset=\"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-content\/uploads\/sites\/233\/2024\/01\/crystallography-socs2-Figure-1.png 789w, https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-content\/uploads\/sites\/233\/2024\/01\/crystallography-socs2-Figure-1-300x225.png 300w, https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-content\/uploads\/sites\/233\/2024\/01\/crystallography-socs2-Figure-1-768x575.png 768w\" sizes=\"auto, (max-width: 789px) 100vw, 789px\" \/><\/a>\n\t\t\t<\/div><\/figure><figure class='gallery-item'>\n\t\t\t<div class='gallery-icon landscape'>\n\t\t\t\t<a href='https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-content\/uploads\/sites\/233\/2024\/01\/crystallography-socs2-Figure-2_200dpi.jpg'><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"678\" src=\"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-content\/uploads\/sites\/233\/2024\/01\/crystallography-socs2-Figure-2_200dpi-1024x678.jpg\" class=\"attachment-large size-large\" alt=\"Fig 2. Identification of arsenic as a source of experimental phasing power\" srcset=\"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-content\/uploads\/sites\/233\/2024\/01\/crystallography-socs2-Figure-2_200dpi-1024x678.jpg 1024w, https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-content\/uploads\/sites\/233\/2024\/01\/crystallography-socs2-Figure-2_200dpi-300x199.jpg 300w, https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-content\/uploads\/sites\/233\/2024\/01\/crystallography-socs2-Figure-2_200dpi-768x508.jpg 768w, https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-content\/uploads\/sites\/233\/2024\/01\/crystallography-socs2-Figure-2_200dpi.jpg 1491w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/a>\n\t\t\t<\/div><\/figure><figure class='gallery-item'>\n\t\t\t<div class='gallery-icon landscape'>\n\t\t\t\t<a href='https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-content\/uploads\/sites\/233\/2024\/01\/crystallography-socs2-Figure-3_200dpi.png'><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"694\" src=\"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-content\/uploads\/sites\/233\/2024\/01\/crystallography-socs2-Figure-3_200dpi-1024x694.png\" class=\"attachment-large size-large\" alt=\"Fig 3. The structure of DMSO-treated SOCS2:EloC:EloB.\" srcset=\"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-content\/uploads\/sites\/233\/2024\/01\/crystallography-socs2-Figure-3_200dpi-1024x694.png 1024w, https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-content\/uploads\/sites\/233\/2024\/01\/crystallography-socs2-Figure-3_200dpi-300x203.png 300w, https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-content\/uploads\/sites\/233\/2024\/01\/crystallography-socs2-Figure-3_200dpi-768x521.png 768w, https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-content\/uploads\/sites\/233\/2024\/01\/crystallography-socs2-Figure-3_200dpi.png 1478w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/a>\n\t\t\t<\/div><\/figure><figure class='gallery-item'>\n\t\t\t<div class='gallery-icon landscape'>\n\t\t\t\t<a href='https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-content\/uploads\/sites\/233\/2024\/01\/crystallography-socs2-Figure-4.png'><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"259\" src=\"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-content\/uploads\/sites\/233\/2024\/01\/crystallography-socs2-Figure-4-1024x259.png\" class=\"attachment-large size-large\" alt=\"Fig 4. Mechanism for dimethylarsenic modification of cysteine residues proposed by Maignan et al.\" srcset=\"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-content\/uploads\/sites\/233\/2024\/01\/crystallography-socs2-Figure-4-1024x259.png 1024w, https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-content\/uploads\/sites\/233\/2024\/01\/crystallography-socs2-Figure-4-300x76.png 300w, https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-content\/uploads\/sites\/233\/2024\/01\/crystallography-socs2-Figure-4-768x195.png 768w, https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-content\/uploads\/sites\/233\/2024\/01\/crystallography-socs2-Figure-4-1536x389.png 1536w, https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-content\/uploads\/sites\/233\/2024\/01\/crystallography-socs2-Figure-4-2048x519.png 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/a>\n\t\t\t<\/div><\/figure>\n\t\t<\/div>\n\n","protected":false},"excerpt":{"rendered":"<p>Our new paper on crystallography of SOCS2-EloB-EloC complex by Arsenic SAD is now published in PLoS One. Read our paper.<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[21,4],"tags":[],"class_list":["post-2692","post","type-post","status-publish","format-standard","hentry","category-21","category-news"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/posts\/2692","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/comments?post=2692"}],"version-history":[{"count":2,"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/posts\/2692\/revisions"}],"predecessor-version":[{"id":4879,"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/posts\/2692\/revisions\/4879"}],"wp:attachment":[{"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/media?parent=2692"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/categories?post=2692"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/tags?post=2692"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}