{"id":2581,"date":"2016-11-04T13:39:00","date_gmt":"2016-11-04T13:39:00","guid":{"rendered":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/?p=2581"},"modified":"2025-01-05T22:30:44","modified_gmt":"2025-01-05T22:30:44","slug":"vhl-inhibitor-vh298-as-novel-chemical-probe-of-the-hypoxia-signalling-pathway","status":"publish","type":"post","link":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/2016\/11\/04\/vhl-inhibitor-vh298-as-novel-chemical-probe-of-the-hypoxia-signalling-pathway\/","title":{"rendered":"VHL inhibitor VH298 as novel chemical probe of the hypoxia signalling pathway"},"content":{"rendered":"<p><\/p>\n\n\n<p>Our paper characterising VHL inhibitor VH298 as novel chemical probe of the hypoxia signalling pathway is now published in Nature Communications.<\/p>\n\n\n\n<p><a href=\"http:\/\/dx.doi.org\/10.1038\/ncomms13312\">Read our open access article<\/a>.<\/p>\n\n\n\n<p>Featured in the\u00a0<a href=\"https:\/\/app.dundee.ac.uk\/news\/2016\/molecular-commando-identified-to-tackle-hypoxia-pathway.php\">UoD<\/a> News websites<\/p>\n\n\n\n<p><a href=\"http:\/\/www.chemicalprobes.org\/vh298\">Access VH298 from the Chemical Probes portal<\/a>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Related Links<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"http:\/\/dx.doi.org\/10.1038\/ncomms13312\" target=\"_blank\" rel=\"noreferrer noopener\">Article | OPEN Potent and selective chemical probe of hypoxic signalling downstream of HIF-\u03b1 hydroxylation via VHL inhibition<\/a><\/li>\n\n\n\n<li><a href=\"http:\/\/www.drugdiscoverytoday.com\/view\/45004\/molecular-commando-identified-to-tackle-hypoxia-pathway\/\" target=\"_blank\" rel=\"noreferrer noopener\">Drug Discovery Today news: `Molecular commando\u2019 identified to tackle hypoxia pathway<\/a><\/li>\n\n\n\n<li><a href=\"http:\/\/www.ub.edu\/web\/ub\/en\/menu_eines\/noticies\/2016\/11\/027.html\" target=\"_blank\" rel=\"noreferrer noopener\">New therapeutic target for diseases caused by lack of oxygen<\/a><\/li>\n\n\n\n<li><a href=\"http:\/\/www.chemicalprobes.org\/vh298\" target=\"_blank\" rel=\"noreferrer noopener\">VH298 on the Chemical Probes Portal<\/a><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Our paper characterising VHL inhibitor VH298 as novel chemical probe of the hypoxia signalling pathway is now published in Nature Communications. Read our open access article. Featured in the\u00a0UoD News websites Access VH298 from the Chemical Probes portal. Related Links<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20,4],"tags":[],"class_list":["post-2581","post","type-post","status-publish","format-standard","hentry","category-20","category-news"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/posts\/2581","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/comments?post=2581"}],"version-history":[{"count":0,"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/posts\/2581\/revisions"}],"wp:attachment":[{"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/media?parent=2581"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/categories?post=2581"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/tags?post=2581"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}