{"id":435,"date":"2023-11-02T14:43:49","date_gmt":"2023-11-02T14:43:49","guid":{"rendered":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/?page_id=435"},"modified":"2026-01-26T14:15:36","modified_gmt":"2026-01-26T14:15:36","slug":"protac-ac-bi-team","status":"publish","type":"page","link":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/group\/protac-ac-bi-team\/","title":{"rendered":"PROTAC collaboration with Boehringer Ingelheim (AC-BI Team)"},"content":{"rendered":"

PROTAC collaboration with Boehringer Ingelheim<\/h2>\n

The AC-BI collaboration team is a multi-disciplinary team which was formally established in 2016, bringing together our expertise in targeted protein degradation with Boehringer Ingelheim\u2019s expertise in Drug Discovery and clinical development of new therapeutic agents. They are focussed on translating fundamental academic discoveries for the benefit of cancer patients through the development of proteolysis targeting chimeras (PROTACs). The team\u2019s structure-guided approach has allowed them to drug previously \u201cundruggable\u201d cancer targets, leading to the development of highly selective and potent first-in-class PROTACs against proteins such as SMARCA2 and KRAS.<\/p>\n

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\"Stefan
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<\/a>
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Person<\/p>\n

Stefan Djukic<\/a><\/div>\n

Scientist in Structural biology\/ Biophysics<\/p>\n<\/p><\/div>\n<\/article>\n

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<\/a>
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Person<\/p>\n

Elizabeth Hogg<\/a><\/div>\n

Scientist in Cell Biology<\/p>\n<\/p><\/div>\n<\/article>\n

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\"Natalia
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<\/a>
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Person<\/p>\n

Natalia Karolak<\/a><\/div>\n

Scientist in Structural biology\/ Biophysics<\/p>\n<\/p><\/div>\n<\/article>\n

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\"\"
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<\/a>
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Person<\/p>\n

Gemma Little<\/a><\/div>\n

Scientist in Medicinal \/ Organic Chemistry<\/p>\n<\/p><\/div>\n<\/article>\n

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\"Elisha
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<\/a>
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Person<\/p>\n

Elisha McCory<\/a><\/div>\n

Scientist in Cell Biology<\/p>\n<\/p><\/div>\n<\/article>\n

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\"Mokhitli
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<\/a>
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Person<\/p>\n

Mokhitli Morake<\/a><\/div>\n

Scientist in Medicinal \/ Organic Chemistry<\/p>\n<\/p><\/div>\n<\/article>\n

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\"Ilaria
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<\/a>
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Person<\/p>\n

Ilaria Puoti<\/a><\/div>\n

Scientist in Cellular Biomarker and Proteomics<\/p>\n<\/p><\/div>\n<\/article>\n

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\"Manon
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<\/a>
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Person<\/p>\n

Manon Sturbaut<\/a><\/div>\n

Scientist in Medicinal \/ Organic Chemistry<\/p>\n<\/p><\/div>\n<\/article>\n

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\"\"
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<\/a>
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Person<\/p>\n

Lisa Thomson<\/a><\/div>\n

Scientist in Cell Biology<\/p>\n<\/p><\/div>\n<\/article>\n

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\"\"
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<\/a>
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Person<\/p>\n

Jeff Wong<\/a><\/div>\n

Scientist in Medicinal \/ Organic Chemistry<\/p>\n<\/p><\/div>\n<\/article>\n

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\n <\/p>\n
\"Qingzhi
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<\/a>
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Person<\/p>\n

Qingzhi Zhang<\/a><\/div>\n

Scientist in Medicinal \/ Organic Chemistry<\/p>\n<\/p><\/div>\n<\/article>\n

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\"Petr
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<\/a>
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Person<\/p>\n

Petr Zhmurov<\/a><\/div>\n

Scientist in Medicinal \/ Organic Chemistry<\/p>\n<\/p><\/div>\n<\/article><\/div>\n","protected":false},"excerpt":{"rendered":"

PROTAC collaboration with Boehringer Ingelheim The AC-BI collaboration team is a multi-disciplinary team which was formally established in 2016, bringing together our expertise in targeted protein degradation with Boehringer Ingelheim\u2019s expertise in Drug Discovery and clinical development of new therapeutic agents. They are focussed on translating fundamental academic discoveries for the benefit of cancer patients […]<\/p>\n","protected":false},"author":1,"featured_media":3808,"parent":188,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-435","page","type-page","status-publish","has-post-thumbnail","hentry"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/pages\/435","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/comments?post=435"}],"version-history":[{"count":3,"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/pages\/435\/revisions"}],"predecessor-version":[{"id":5020,"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/pages\/435\/revisions\/5020"}],"up":[{"embeddable":true,"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/pages\/188"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/media\/3808"}],"wp:attachment":[{"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/media?parent=435"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}