{"id":3029,"date":"2024-03-04T15:37:55","date_gmt":"2024-03-04T15:37:55","guid":{"rendered":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/?page_id=3029"},"modified":"2026-01-26T14:32:36","modified_gmt":"2026-01-26T14:32:36","slug":"gajanan-sathe","status":"publish","type":"page","link":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/group\/gajanan-sathe\/","title":{"rendered":"Gajanan Sathe"},"content":{"rendered":"<div class=\"panel \">\n<figure class=\"wp-block-image size-large\"><source class=\"lazyload\" srcset=\"https:\/\/sites.dundee.ac.uk\/wp-content\/uploads\/sites\/233\/2024\/03\/Gajanan_Sathe-web.webp\" alt=\"Gajanan Sathe\" type=\"image\/webp\"><source class=\"lazyload\" srcset=\"https:\/\/sites.dundee.ac.uk\/wp-content\/uploads\/sites\/233\/2024\/03\/Gajanan_Sathe-web.jpg\" alt=\"Gajanan Sathe\" type=\"image\/jpeg\"><img decoding=\"async\" src=\"https:\/\/sites.dundee.ac.uk\/wp-content\/uploads\/sites\/233\/2024\/03\/Gajanan_Sathe-web.jpg\" alt=\"Gajanan Sathe\"><br \/>\n  <\/source><\/source><\/figure>\n<\/p><\/div>\n<h2>Degree<\/h2>\n<p>BSc Biotechnology\u00a0<a href=\"https:\/\/uod-servicedesk.topdesk.net\/tas\/secure\/incident?action=lookup&amp;lookup=naam&amp;lookupValue=2004-2007\">2004-2007<\/a>, University of Pune<br \/>\nMSc Biotechnology\u00a0<a href=\"https:\/\/uod-servicedesk.topdesk.net\/tas\/secure\/incident?action=lookup&amp;lookup=naam&amp;lookupValue=2007-2009\">2007-2009<\/a>, University of Pune<br \/>\nPhD Institute of Bioinformatics Bangalore &amp; Jhons Hopkins university Baltimore\u00a0<a href=\"https:\/\/uod-servicedesk.topdesk.net\/tas\/secure\/incident?action=lookup&amp;lookup=naam&amp;lookupValue=2010-2017\">2010-2017<\/a><\/p>\n<h2>Staff email<\/h2>\n<p><a href=\"mailto:gsathe001@dundee.ac.uk\">gsathe001@dundee.ac.uk<\/a><\/p>\n<h2>Profile<\/h2>\n<p>Gajanan obtained his Ph.D. from the Institute of Bioinformatics in Bangalore and\u00a0<wbr><\/wbr>Johns Hopkins University in Baltimore, USA. His doctoral research focused on employing mass\u00a0<wbr><\/wbr>spectrometry-based proteomics to delve into the signalling mechanisms underlying the anticancer\u00a0<wbr><\/wbr>properties of curcumin in head and neck cancer. During his time at Johns Hopkins University, he\u00a0<wbr><\/wbr>utilized mass spectrometry-based proteomics technology to pinpoint biomarkers for Alzheimer\u2019s\u00a0<wbr><\/wbr>disease using samples from cerebrospinal fluid and brain tissue.<\/p>\n<p>Upon his return to India, Gajanan played a pivotal role in establishing mass spectrometry facilities\u00a0<wbr><\/wbr>for proteomics at the National Institute of Mental Health and Neuroscience in Bangalore. In\u00a0<wbr><\/wbr>December 2020, he joined Professor Sapkota\u2019s lab as a postdoctoral researcher. In this role, he\u00a0<wbr><\/wbr>refined the protocol for global ubiquitination analysis and utilized it to decipher the mechanisms of\u00a0<wbr><\/wbr>targeted protein degradation. This protocol proved instrumental in identifying ubiquitination\u00a0<wbr><\/wbr>mediated by Affinity-directed Protein Missile (AdPROM) on target proteins, as well as ubiquitination\u00a0<wbr><\/wbr>facilitated by PROTACs on target proteins. Additionally, he implemented a phosphoproteomics\u00a0<wbr><\/wbr>workflow to explore off-target effects of the Affinity-directed phosphatase (AdPhosphatase)\u00a0<wbr><\/wbr>system. Moreover, he utilized a global phosphoproteomics workflow to investigate the role of\u00a0<wbr><\/wbr>protein phosphatase 2. His research also delved into targeted dephosphorylation of TAU and its\u00a0<wbr><\/wbr>implications on microtubule binding and aggregation. Outside the lab, he enjoys traveling and\u00a0<wbr><\/wbr>exploring new places.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Degree BSc Biotechnology\u00a02004-2007, University of Pune MSc Biotechnology\u00a02007-2009, University of Pune PhD Institute of Bioinformatics Bangalore &amp; Jhons Hopkins university Baltimore\u00a02010-2017 Staff email gsathe001@dundee.ac.uk Profile Gajanan obtained his Ph.D. from the Institute of Bioinformatics in Bangalore and\u00a0Johns Hopkins University in Baltimore, USA. His doctoral research focused on employing mass\u00a0spectrometry-based proteomics to delve into the signalling [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":188,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-3029","page","type-page","status-publish","hentry"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/pages\/3029","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/comments?post=3029"}],"version-history":[{"count":1,"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/pages\/3029\/revisions"}],"predecessor-version":[{"id":4620,"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/pages\/3029\/revisions\/4620"}],"up":[{"embeddable":true,"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/pages\/188"}],"wp:attachment":[{"href":"https:\/\/sites.dundee.ac.uk\/alessio-ciulli\/wp-json\/wp\/v2\/media?parent=3029"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}